918867-88-6
中文名称
坦索罗辛杂质A
英文名称
TaMsulosin EP IMpurity A
CAS
918867-88-6
分子式
C30H40N2O7S
分子量
572.71
MOL 文件
918867-88-6.mol
更新日期
2025/04/18 15:00:32
918867-88-6 结构式
基本信息
中文别名
坦索罗辛杂质A坦洛新EP杂质A
盐酸坦索罗辛杂质A
坦索罗辛EP杂质A
坦洛新杂质A (EP)
坦索罗辛欧洲药典杂质A
坦索罗辛杂质A (EP)
坦索罗辛EP杂质A HCI
英文别名
TaMsulosin EP IMpurity ATamsulosin Impurity A HCl
Tamsulosine Bromo Impurity
Tamsulosin EP Impurity A HCl
Tamsulosin EP Impurity A Hydrochloride
Tamsulosin Impurity 10(Tamsulosin EP Impurity A)
5-((R)-2-{bis-[2-(2-ethoxyphenoxy)ethyl]amino}-propyl)-2-methoxybenzenesulfonamide
5-[(2R)-2-[bis[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy benzene sulfonamide
Tamsulosin Impurity 1/Tamsulosin EP Impurity A HCl/5-[(2R)-2-[bis[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy benzene sulfonamide Hydrochloride
所属类别
分析化学：对照品物理化学性质
沸点717.4±70.0 °C(Predicted)
密度1.185±0.06 g/cm3(Predicted)
溶解度DMSO (Slightly), Methanol (Slightly)
酸度系数(pKa)10.07±0.60(Predicted)
形态Sticky Solid
颜色Off-White to Pale Beige
InChIKeyOTXBFJHUSODSBC-HSZRJFAPSA-N
SMILESC1(S(N)(=O)=O)=CC(C[C@H](N(CCOC2=CC=CC=C2OCC)CCOC2=CC=CC=C2OCC)C)=CC=C1OC
应用领域
用途一
N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin (Tamsulosin EP Impurity A) is derived from 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide (A628695), which is a precursor in the synthesis of Tamsulosin (T006350) and other alpha-andregenic antagonists. (R)-Tamsulosin is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.