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93106-59-3

中文名称 盐酸恩诺沙星
英文名称 ENROFLOXAIN HYDROCHLORIDE
CAS 93106-59-3
分子式 C19H23ClFN3O3
分子量 395.856
MOL 文件 93106-59-3.mol
更新日期 2023/10/30 13:34:02
93106-59-3 结构式 93106-59-3 结构式

基本信息

中文别名
恩诺沙星单盐酸盐
英文别名
ENROFLOXAIN HYDROCHLORIDE
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI)
所属类别
医药中间体:原料药中间体

物理化学性质

储存条件-20°C储存
溶解度H2O: 2 mg/mL, clear (Warmed)
形态Solid
颜色White to off-white
水溶解性Water : 7.14 mg/mL (Need ultrasonic)
InChIInChI=1S/C19H22FN3O3.ClH/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12;/h9-12H,2-8H2,1H3,(H,25,26);1H
InChIKeyPZJWYUDBXNNVLZ-UHFFFAOYSA-N
SMILESN1(C2CC2)C2=C(C=C(F)C(N3CCN(CC)CC3)=C2)C(=O)C(C(O)=O)=C1.[H]Cl

安全数据

危险性符号(GHS)健康危害 (GHS08)有害 (GHS07)
GHS08,GHS07
警示词危险
危险性描述H302,H317,H334
盐酸恩诺沙星价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2026/06/05HY-B0502AR盐酸恩诺沙星
Enrofloxacin monohydrochloride (Standard)
93106-59-310 mg340元
2026/06/05HY-B0502AR盐酸恩诺沙星
Enrofloxacin monohydrochloride (Standard)
93106-59-325 mg660元
2026/06/05HY-B0502AR盐酸恩诺沙星
Enrofloxacin monohydrochloride (Standard)
93106-59-350 mg1000元

常见问题列表

生物活性
Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 是一种有效的抗生素,作用于 Mycoplasma bovis,MIC90 为 0.312 μg/ mL。
靶点

MIC90: 0.312 μg/mL ( Mycoplasma bovis )

体外研究

Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The antibiotic susceptibility profiles of the Hungarian strains are consistent within the tested group of fluoroquinolones. Three isolates (MYC44, MYC45 and MYC46) have high MIC values (≥10 μg/mL) to Enrofloxacin, while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0.312 or 0.625 μg/mL.

体内研究

Mice (n=80) undergo transient middle cerebral artery occlusion (MCAo) with reperfusion after 60 minutes. After MCAo, animals are randomly assigned to receive either a daily preventive medication (n=26, Enrofloxacin) starting at the day of MCAo or a therapeutic medication (n=25; Enrofloxacin) after diagnosis of lung infection. Standard treatment started immediately after the appearance of clinical signs (general health score>6) usually between day 4 and 6 after stroke. Both, preventive and standard antibiotic treatment using Enrofloxacin improve survival in a similar way compared with placebo treatment.

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