93363-11-2

中文名称 3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide

英文名称 3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide

CAS 93363-11-2

分子式 C12H11N3OS

分子量 245.3

MOL 文件 93363-11-2.mol

更新日期 2023/03/17 20:03:08

93363-11-2 结构式

基本信息物理化学性质图谱信息 3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide价格(试剂级) 常见问题列表

基本信息

中文别名

化合物 T10159
化合物48740 RP

英文别名

48740Rp
Rp 55779
48740 Rp
RP-48740
3-(3-Pyridinyl)-1H-pyrrolo[1,2-c]thiazole-7-carboxamide
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide
1H,3H-Pyrrolo(1,2-C)thiazole-7-carboxamide, 3-(3-pyridinyl)-

物理化学性质

沸点516.4±50.0 °C(Predicted)

密度1.49±0.1 g/cm3(Predicted)

储存条件-20°C储存

溶解度溶于二甲基亚砜

酸度系数(pKa)16.43±0.40(Predicted)

图谱信息

3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide(93363-11-2)核磁图(¹HNMR)

3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide价格(试剂级)

报价日期	产品编号	产品名称	CAS号	包装	价格
2025/02/08	HY-100153	48740 RP	93363-11-2	1 mg	7200元

常见问题列表

生物活性

48740 RP (RP-55778) 是一种血小板激活因子 (PAF) 拮抗剂。

靶点

PAF

体内研究

48740 RP (RP-55778) is a platelet-activating factor (PAF) antagonist. In animals treated with 48740 RP only, the number of platelets is increased at a time corresponding to 2 and 4 h after the exposure to lipopolysaccharide (LPS) and the number of eosinophils is also slightly increased. Treatment with 48740 RP in combination with the LPS exposure does not influence the increase in neutrophils seen 2 and 4 h after exposure. At 24 h the increase in the number of neutrophils is about half that in control animals. No effects are found on the LPS-induced increase in number of platelets. In animals pretreated with 48740 RP, there is a significant reduction in capillary permeability.