946123-12-2
中文名称
Coumarin 343 X NHS ester
英文名称
Coumarin 343 X NHS ester
CAS
946123-12-2
分子式
C26H29N3O7
分子量
495.52
MOL 文件
946123-12-2.mol
更新日期
2025/04/30 10:38:10
946123-12-2 结构式
物理化学性质
外观性状外观 : 黄色固体
ex/em : 437/477 nm
消光系数(ε) : 39000 L⋅mol−1⋅cm−1
量子产率(Φ) : 0.63
ex/em : 437/477 nm
消光系数(ε) : 39000 L⋅mol−1⋅cm−1
量子产率(Φ) : 0.63
密度1.41±0.1 g/cm3(Predicted)
溶解度易溶于DCM, DMSO, DMF
酸度系数(pKa)12.88±0.20(Predicted)
外观Yellow solid
ε(消光系数)39000 L⋅mol−1⋅cm−1
Φ(量子产率)0.63
激发峰(Ex)/发射峰(Em)437/477 nm
InChIInChI=1S/C26H29N3O7/c30-20-9-10-21(31)29(20)36-22(32)8-2-1-3-11-27-25(33)19-15-17-14-16-6-4-12-28-13-5-7-18(23(16)28)24(17)35-26(19)34/h14-15H,1-13H2,(H,27,33)
InChIKeyUTYUORAKIFFNAS-UHFFFAOYSA-N
SMILESC(ON1C(=O)CCC1=O)(=O)CCCCCNC(C1=CC2=CC3=C4C(=C2OC1=O)CCCN4CCC3)=O
应用领域
用途一
Blue emitting Coumarin 343 dye can form a FRET pair with fluorescein (FAM). An amine reactive form, activated NHS ester._x000D_
This amine-reactive NHS ester contains an aminohexanoyl linker between the fluorophore, and the reactive group. This linker provides better solubility and spatial separation between the fluorophore, and the target molecule being labeled.