妥洛帕泛
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- CAS号:
- 116289-53-3
- 英文名:
- Tulopafant
- 英文别名:
- Tulopafant;1H,3H-Pyrrolo[1,2-c]thiazole-7-carboxamide, N-(3-benzoylphenyl)-3-(3-pyridinyl)-, (+)-
- 中文名:
- 妥洛帕泛
- 中文别名:
- 妥洛帕泛;化合物 T17178
- CBNumber:
- CB01117930
- 分子式:
- C25H19N3O2S
- 分子量:
- 425.51
- MOL File:
- 116289-53-3.mol
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妥洛帕泛化学性质
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沸点:
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613.3±55.0 °C(Predicted)
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密度:
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1.32±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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13.51±0.70(Predicted)
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妥洛帕泛性质、用途与生产工艺
Tulopafant 是血小板激活因子 (PAF) 拮抗剂。
Preincubation of neutrophils with Tulopafant (RP 59227) results in a concentration-dependent decrease in chemiluminescence produced by PAF primed cells.
Tulopafant (RP 59227) effectively reduces myocardial infarct size and reduces the incidence of ischemia and reperfusion-induced arrhythmias in barbital-anesthetized dogs.Histological examination reveals marked diminution of both interstitial hemorrhage and deposition of platelet and granulocytes in capillaries of cardiac xenografts when recipient animals are pretreated with Tulopafant.
妥洛帕泛
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116289-53-3, 妥洛帕泛 相关搜索:
- C25H19N3O2S
- 化合物 T17178
- 妥洛帕泛
- 116289-53-3
- 1H,3H-Pyrrolo[1,2-c]thiazole-7-carboxamide, N-(3-benzoylphenyl)-3-(3-pyridinyl)-, (+)-
- Tulopafant