多克隆抗体
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- CAS号:
- 138579-66-5
- 英文名:
- GALANTIDE
- 英文别名:
- M15;GALANTIDE;M 15 (peptide);Galantide, M15;GalantideGalanti;GALANTIDE| Galantide;Galantide, ≥90% (HPLC);GWTLNSAGYLLGPQQFFGLM-NH2;Galanin(1-13)-substance P(5-11);Rabbit Anti-PKA R2/PKA IIÎ
- 中文名:
- 多克隆抗体
- 中文别名:
- 多克隆抗体;GALANTIDE肽;GALANTIDE,可逆甘丙肽受体拮抗剂;GALANTIDE (甘丙肽受体拮抗剂);兔抗PKA R2/PKA II&ICIRC
- CBNumber:
- CB0173935
- 分子式:
- C104H151N25O26S
- 分子量:
- 2199.53
- MOL File:
- 138579-66-5.mol
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多克隆抗体化学性质
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沸点:
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2345.4±65.0 °C(Predicted)
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密度:
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1.305±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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形态:
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Solid
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酸度系数(pKa):
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9.82±0.15(Predicted)
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多克隆抗体性质、用途与生产工艺
Galantide 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂，是一种由甘丙肽和 P 物质片段组成的肽段，在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide 似乎与单一的 SP 受体群结合 (KD~40 nM)。
Galantide do not activate the K
+
conductance but produces a concentration-dependent antagonism (IC
50
=4 nM) of the galanin-induced increase in K
+
conductance. Galantide acts like galanin and inhibits the voltage-dependent Ba2+ current (IBa). The inhibition of IBa also is concentration dependent (IC
50
=16 nM) and the maximum inhibition produced by galantide is approximately 40%.
Intracerebroventricular injection of galanin (5 micrograms/rat) inhibited sexual behavior in experienced male rats--without producing any other locomotor or behavioral deficit-, injection of the galanin antagonist, galantide, by the same route (1 or 2 micrograms/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. Galantide ameliorates mild acute pancreatitis (AP). Galantide significantly reduces AP-induced hyperenzymemia by 41–49%. Galantide has been found to improve social memory in 'socialrecognition' test when i.c.v. administered at doses varying from 6-6000 nM.
多克隆抗体
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-P0262 | 多克隆抗体
Galantide | 138579-66-5 | 500μg | 1400元 |
| 2024/01/25 | HY-P0262 | 多克隆抗体
Galantide | 138579-66-5 | 1mg | 2400元 |
多克隆抗体
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138579-66-5, 多克隆抗体 相关搜索:
- Peptide
- Galanin receptor
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- 细胞生物学
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- BioChemical
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- Biochemicals and Reagents
- C104H151N25O26S
- C104H151N25O26S1
- GALANTIDE,可逆甘丙肽受体拮抗剂
- GALANTIDE (甘丙肽受体拮抗剂)
- 兔抗PKA R2/PKA II&ICIRC
- GALANTIDE肽
- 多克隆抗体
- 138579-66-5
- Rabbit Anti-PKA R2/PKA IIÎ
- Galantide, ≥90% (HPLC)
- GALANTIDE| Galantide
- GalantideGalanti
- Galantide, M15
- Galanin (1-13)-Substance P (5-11) aMide
Galantide, M15
- M 15 (peptide)
- GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-*LEU -LEU-GLY-PR
- gly-trp-thr-leu-asn-ser-ala-gly-tyr-*leu-leu-gly-
- M15
- H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
- GWTLNSAGYLLGPQQFFGLM-NH2
- GALANIN (1-13)-SUBSTANCE P (5-11) AMIDE
- GALANTIDE
- GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
- GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET AMIDE
- Galanin (1-13)-Substance P (5-11), amide, Galantide
- L-Methioninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
- Gly-L-Trp-L-Thr-L-Leu-L-Asn-L-Ser-L-Ala-Gly-L-Tyr-L-Leu-L-Leu-Gly-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2
- Galanin(1-13)-substance P(5-11)