环二磷酸腺苷核酸糖
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- CAS号:
- 119340-53-3
- 英文名:
- CADP-RIBOSE
- 英文别名:
- CADPR;C13050;CADP-RIBOSE;CYCLIC ADPR;CADPR SODIUM SALT;CYCLIC ADP-RIBOSE;cADP-Ribose (cADPR);ADP-CYCLO-[N1:1'']-RIBOSE;CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE;Cyclic ADP?ribose,Cyclic ADP ?ribose
- 中文名:
- 环二磷酸腺苷核酸糖
- 中文别名:
- 环ADP核糖;环状ADP核糖;环二磷酸腺苷核酸糖;化合物 T19253
- CBNumber:
- CB0236872
- 分子式:
- C15H21N5O13P2
- 分子量:
- 541.3
- MOL File:
- 119340-53-3.mol
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环二磷酸腺苷核酸糖化学性质
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沸点:
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934.8±75.0 °C(Predicted)
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密度:
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2.57±0.1 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)
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酸度系数(pKa):
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0.97±0.70(Predicted)
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形态:
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lyophilized powder
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稳定性:
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Hygroscopic
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环二磷酸腺苷核酸糖性质、用途与生产工艺
Cyclic ADP-ribose (cADPR) 是一种有效的钙动员 (calcium mobilization) 第二信使，是通过 ADP-核糖基环化酶从 NAD+ 合成的。Cyclic ADP-ribose 主要通过 Ryanodine 受体介导的内质网释放以及通过 TRPM2 通道开放引起的细胞外流入来增加胞质钙。
Calcium mobilization
TRPM2 channels
Endogenous metabolite
cADPR (20 nM) elicits a large rapid Ca
2+
release in sea urchin eggs homogenates.
cADPR (100 µM; 10 min) induces a sustained elevation of intracellular calcium concentration in a subset (64%) of cultured astrocytes.
cADPR (100 µM) and heat (35-38.5 ℃) stimulates oxytocin OT release from the isolated hypothalami of male mice in culture.
cADPR (100 µM; push-pull type of brain microperfusion) elevats OT concentrations in ordinate or subordinate mice.
环二磷酸腺苷核酸糖
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-N7395 | 环二磷酸腺苷核酸糖
Cyclic ADP-ribose | 119340-53-3 | 500μg | 7600元 |
119340-53-3, 环二磷酸腺苷核酸糖 相关搜索:
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- Intracellular Calcium Regulators
- Intracellular Calcium Signaling
- C15H21N5O13P2NH3
- C15H21N5O13P2
- 119340-53-5
- 化合物 T19253
- 环ADP核糖
- 环状ADP核糖
- 环二磷酸腺苷核酸糖
- 119340-53-3
- Cyclic ADP?ribose,Cyclic ADP ?ribose
- Adenosine5'-(trihydrogen diphosphate), 1-b-D-ribofuranosyl-, intramol. P',5''-ester
- Cyclic adenosine 5'-diphosphate ribose ammonium salt
- Adenosine 5'-(trihydrogen diphosphate), 1-β-D-ribofuranosyl-, intramol. P',5''-ester
- cADP-Ribose (cADPR)
DISCONTINUED. Please see A291808.
- CYCLIC ADP-RIBOSE
- CYCLIC ADPR
- CYCLIC ADENOSINE DIPHOSPHATE RIBOSE SODIUM SALT
- CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE
- CYCLIC ADENOSINE 5'-DIPHOSPHATE RIBOSE
- N-ALPHA-D-RIOFURANOSYL-P',5''-ESTER ADENOSINE 5'-(TRIHYDROGEN DIPHOSPHATE)
- cADP-Ribose (cADPR)
- C13050
- ADP-cyclo[N1:1μμ]-ribose, cADP-ribose, cADPR, Cyclic ADPR
- CYCLIC ADP RIBOSE POTENT INTRACELLULAR
- cyclicadenosinediphosphateribose(cadpr),sodiumsalt
- CADPR SODIUM SALT
- ADP-CYCLO-[N1:1'']-RIBOSE
- CADP-RIBOSE
- CADPR