289893-26-1
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- CAS号:
- 289893-26-1
- 英文名:
- AriMocloMol Maleic Acid
- 英文别名:
- BRX220;BRX-220;BRX-345;BRX345.;BRX 220;BRX 345;AriMocloMol Maleic Acid;(2R)-Arimoclomol maleate;(2R)-Arimoclomol Maleic Acid;ARIMOCLOMOL MALEATE (BRX-220)
- 中文名:
- 289893-26-1
- 中文别名:
- 化合物ARIMOCLOMOL MALEATE
- CBNumber:
- CB02695637
- 分子式:
- C18H24ClN3O7
- 分子量:
- 429.85206
- MOL File:
- 289893-26-1.mol
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289893-26-1化学性质
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熔点:
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>131°C (dec.)
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储存条件:
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Amber Vial, -20°C Freezer, Under inert atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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289893-26-1性质、用途与生产工艺
Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。Arimoclomol 通过增强 Hsp 表达来保护运动神经元，从而通过泛素-蛋白酶体系统直接影响蛋白质聚集及清除错误折叠和装配的蛋白。
Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis.
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Animal Model:
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Male Wistar rats weighing 240 to 270 g
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Dosage:
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20 mg/kg
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Administration:
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Administered intragastrically, for 5 days
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Result:
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Had a protective effect against CCK-induced acute pancreatitis.
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289893-26-1
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2021/03/30 | S0860 | 289893-26-1
Arimoclomol maleate | 289893-26-1 | 25mg | 8018.01元 |
289893-26-1, 289893-26-1 相关搜索:
- Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- 药靶配体
- 抑制剂
- C18H24ClN3O7
- 化合物ARIMOCLOMOL MALEATE
- 289893-26-1
- (2R)-Arimoclomol Maleic Acid
- ARIMOCLOMOL MALEATE; BRX-220; BRX 220; BRX220; BRX-345; BRX 345; BRX345.
- BRX 220
- BRX 345
- BRX220
- BRX-220
- BRX-345
- BRX345.
- ARIMOCLOMOL MALEATE (BRX-220)
- (2R)-Arimoclomol maleate
- AriMocloMol Maleic Acid