(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
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- CAS号:
- 118021-35-5
- 英文名:
- O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
- 英文别名:
- L-4-OXALYSINE HCL;H-SER(ETNH2)-OH HCL;H-LYS[*4(<-O)]-OH HCL;4-OXY-L-LYSINE HYDROCHLORIDE;L-4-Oxalysine (hydrochloride);O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE;O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE USP/EP/BP;(2S)-2-amino-3-(2-aminoethoxy)propanoicacid,hydrochloride;(S)-(+)-2-AMINO-3-(2-AMINOETHOXY)PROPANOIC ACID, MONOHYDROCHLORIDE;(S)-(+)-2-AMINO-3-(2-AMINOETHOXY)-PROPAN OIC ACID HYDROCHLORIDE, 98%
- 中文名:
- (S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
- 中文别名:
- L-4-噁溶菌素盐酸盐;O-(2-氨乙基)-L-丝氨酸盐酸盐;O-(2-氨基乙基)-L-丝氨酸盐酸盐;间-(2-氨基乙基)-L-丝氨酸盐酸盐;(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸;(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸 单盐酸盐
- CBNumber:
- CB0297079
- 分子式:
- C5H13ClN2O3
- 分子量:
- 184.62
- MOL File:
- 118021-35-5.mol
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(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸化学性质
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熔点:
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212-216 °C(lit.)
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比旋光度:
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+4.0～+8.0°(c=10,dilHCl)(D/20)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸性质、用途与生产工艺
L-4-Oxalysine hydrochloride是从中国的链霉菌培养基中分离的天然物质，具有抗癌活性。
Alpha-fetoprotein (AFP) is expressed in BEL-7404 human hepatoma cells and L-4-Oxalysine suppresses AFP mRNA expression in the cells. L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor.
Tbe ultrastructural efects of different doses of L-4-Oxalysine on hepatocytes in mice are most serious at day 1 after stopping treatment. Mice are given ig L-4-oxalysine (I-677) 10, 50, and 100 mg/kg for 7 d. On day 8 the hepatocytes show accumulation of lipid droplets followed by loss of matrices in cytoplasm. The total area of lipid droplets is far less than 25% of mean section of hepatocytes. The injury of mitochondria and RER is only found in the groups of medium and high dose. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma.
(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-U00097 | (S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
L-4-Oxalysine hydrochloride | 118021-35-5 | 1mg | 1000元 |
(S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
生产厂家
118021-35-5, (S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸 相关搜索:
- Unnatural Amino Acid Derivatives
- Peptide Synthesis
- Others
- 高端化学
- Specialty Synthesis
- Unnatural Amino Acid Derivatives
- Others
- Peptide Synthesis
- C5H12N2O3HCl
- H2NCH2CH2OCH2CHNH2CO2HHCl
- C5H13ClN2O3
- O-(2-氨基乙基)-L-丝氨酸盐酸盐
- L-4-噁溶菌素盐酸盐
- 间-(2-氨基乙基)-L-丝氨酸盐酸盐
- (S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸 单盐酸盐
- O-(2-氨乙基)-L-丝氨酸盐酸盐
- (S)-(+)-2-氨基-3-(2-氨基乙氧基)丙酸赖氨酸
- 118021-35-5
- O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE USP/EP/BP
- (2S)-2-amino-3-(2-aminoethoxy)propanoicacid,hydrochloride
- 4-OXY-L-LYSINE HYDROCHLORIDE
- (S)-(+)-2-AMINO-3-(2-AMINOETHOXY)-PROPAN OIC ACID HYDROCHLORIDE, 98%
- L-4-Oxalysine (hydrochloride)
- O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
- (S)-(+)-2-AMINO-3-(2-AMINOETHOXY)PROPANOIC ACID, MONOHYDROCHLORIDE
- L-4-OXALYSINE HCL
- H-LYS[*4(<-O)]-OH HCL
- H-SER(ETNH2)-OH HCL