网站主页 >> CAS数据库列表 >> TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
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- CAS号:
- 76622-26-9
- 英文名:
- BAM-22P
- 英文别名:
- BAM22;ADTB1;AP1B1;AP105A;BAM-22P;Peptide E(1-22);BAM 22P acetate;YGGFMRRVGRPEWWMDYQKRYG;BOVINE ADRENAL MEDULLA-22P;BOVINE ADRENAL MEDULLA DOCOSAPEPTIDE
- 中文名:
- TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
- 中文别名:
- 阿片肽BAM-22P
- CBNumber:
- CB0345600
- 分子式:
- C130H184N38O31S2
- 分子量:
- 2839.22
- MOL File:
- 76622-26-9.mol
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TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY化学性质
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密度:
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1.50±0.1 g/cm3(Predicted)
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RTECS号:
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SC6200500
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储存条件:
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-15°C
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溶解度:
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Soluble to 1 mg/ml in H2O
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形态:
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Lyophilized solid
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水溶解性:
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Soluble to 1 mg/ml in water
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TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY性质、用途与生产工艺
BAM-22P 是一种强效的阿片肽，是一种强效的阿片类 (opioid) 激动剂。
Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla. Plasma levels of BAM-22P are determined by a sensitive radioimmunoassay, and the specificity of the assay is confirmed using high-performance liquid chromatography. Plasma BAM-22P levels s cholestatic rats are significantly higher than those in control rats. This increase in plasma BAM-22P levels is completely prevented by adrenalectomy. Adrenal steady-state levels of proenkephalin mRNA, as determined by Northern blot hybridization analyses, are also increased significantly in cholestatic rats. These increases in proenkephalin mRNA levels are not paralleled by changes in adrenal BAM-22P peptide levels, which are similar in cholestatic rats and their respective controls. Similar levels of proenkephalin mRNA expression are observed in innervated and denervated adrenal glands from cholestatic rats, suggesting that the increase in adrenal proenkephalin mRNA levels in acute cholestasis is not due to splanchnic nerve activation. Thus acute cholestasis in the rat is associated with adrenal secretion and accumulation in plasma of the highly potent opioid peptide BAM-22P and an augmentation of adrenal proenkephalin mRNA expression. The increase in plasma BAM-22P levels may contribute substantially to the increase in total circulating opioid activity documented in cholestatic rats. Adrenal gland levels of BAM-22P are similar in BDR and sham-resected rats (BDR, 1.10±0.39 ng/g; sham, 0.93±0.16 ng/g; NS). BAM-22P levels in ANIT-treated and oil-gavaged controls are also similar (ANIT, 2.88±0.29 ng/g; control, 2.75±0.30 ng/g; NS). However, adrenal BAM-22P levels are lower in BDR and sham-resected rats than in ANIT-treated and oil-gavaged controls (P<0.01). Acute cholestasis in the rat is associated with enhanced synthesis and secretion of the proen-kephalin-derived opioid peptide BAM-22P from the adrenal gland.
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2023/03/20 | HY-P1331 | TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
BAM-22P | 76622-26-9 | 500μg | 1800元 |
| 2023/03/20 | HY-P1331 | TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
BAM-22P | 76622-26-9 | 1mg | 2800元 |
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY
生产厂家
76622-26-9, TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY 相关搜索:
- Various Peptides
- Peptide
- 多肽
- 目录肽
- C130H184N38O31S2
- 阿片肽BAM-22P
- 76622-26-9
- BAM 22P acetate
- Glycine, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valylglycyl-L-arginyl-L-prolyl-L-α-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl-
- BAM-22P H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH
- H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY-OH
- BOVINE ADRENAL MEDULLA DOCOSAPEPTIDE
- BOVINE ADRENAL MEDULLA-22P
- BAM-22P
- AP1B1
- AP105A
- ADTB1
- Peptide E(1-22)
- L-Tyr-Gly-Gly-L-Phe-L-Met-L-Arg-L-Arg-L-Val-Gly-L-Arg-L-Pro-L-Glu-L-Trp-L-Trp-L-Met-L-Asp-L-Tyr-L-Gln-L-Lys-L-Arg-L-Tyr-Gly-OH
- BAM22
- YGGFMRRVGRPEWWMDYQKRYG
- TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY