MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
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- CAS号:
- 84746-43-0
- 英文名:
- SCPB
- 英文别名:
- SCPB;MNYLAFPRM-NH2;SMALL CARDIOACTIVE PEPTIDE B;CARDIOACTIVE PEPTIDE B (SMALL);Small Cardioactive Peptide B (SCPB);SCPB
Cardioactive Peptide B (sMall);MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2;MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE;H-MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2;MET-ASN--LEU-ALA-PHE-PRO-ARG-MET (MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE)
- 中文名:
- MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
- 中文别名:
- 小心脏活性肽B;小心脏活性肽B SCPB
- CBNumber:
- CB0681661
- 分子式:
- C52H80N14O11S2
- 分子量:
- 1141.41
- MOL File:
- 84746-43-0.mol
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MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2化学性质
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密度:
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1.41±0.1 g/cm3(Predicted)
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储存条件:
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−20°C
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酸度系数(pKa):
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9.82±0.15(Predicted)
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MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2性质、用途与生产工艺
Small Cardioactive Peptide B (SCPB) 是一种神经活性肽，刺激心脏和鳃组织的颗粒组分中的腺苷酸环化酶 (adenylate cyclase) 活性，EC50 分别为 0.1 和 1.0 μM。
EC50: 0.1 μM (adenylate cyclase, in heart tissues), 1.0 μM (adenylate cyclase, in gill tissues)
Small cardioactive peptide B (SCP
B
) is a neurally active peptide endogenous to
Aplysia
. Small cardioactive peptide B (SCP
B
) possesses cardioexcitatory effects in
Aplysia
and reported a threshold concentration of 0.01 nM for both native and synthetic Small cardioactive peptide B (SCP
B
) stimulated effects on the isolated heart. Effects of Small Cardioactive Peptide B (SCP
B
) on the physiology of the isolated heart and gill preparations from the mollusc Aplysia californica were examined. In addition, the effects of Small Cardioactive Peptide B (SCP
B
) and FMRFamide (Phe-Met-Arg-Phe-NH2) on adenylate cyclase activity are compared in particulate fractions of heart and gill tissues, respectively. Small Cardioactive Peptide B (SCP
B
) is found to exert dose-dependent, reversible changes in cardiac activity when perfused through the isolated heart. The EC
50
values effecting changes in heart rate and force of contraction are 0.03 and 0.3 nM, respectively; minimum concentrations find to effect changes in heart rate and force of contraction are normally 0.001 and 1 pM, respectively. When perfused through the isolated gill, Small Cardioactive Peptide B (SCP
B
) is found to suppress the gill withdrawal response amplitude with a threshold concentration of 0.01 pM and an EC
50
value of 0.03 nM. Suppression of the gill withdrawal response amplitude by Small Cardioactive Peptide B (SCP
B
)is found to be dose dependent and reversible up to a concentration of 1nM. At higher concentrations, the suppression tended to persist irreversibly. Small Cardioactive Peptide B (SCP
B
) stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with an EC
50
of 0.1 and 1.0μM, respectively.
MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-P1495 | MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
Small Cardioactive Peptide B (SCPB) | 84746-43-0 | 1mg | 700元 |
| 2024/01/25 | HY-P1495 | MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
Small Cardioactive Peptide B (SCPB) | 84746-43-0 | 5mg | 2100元 |
MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
生产厂家
84746-43-0, MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2 相关搜索:
- Peptides for Cell Biology
- Peptides and Proteins
- Other Peptides
- Peptide
- 目录多肽
- 多肽
- 目录肽
- BioChemical
- Amino Acids and Peptides
- Biochemicals and Reagents
- Other Peptides
- Peptides
- C52H80N14O11S2
- 小心脏活性肽B SCPB
- 小心脏活性肽B
- 84746-43-0
- L-Methioninamide, L-methionyl-L-asparaginyl-L-tyrosyl-L-leucyl-L-alanyl-L-phenylalanyl-L-prolyl-L-arginyl-
- Small Cardioactive Peptide B (SCPB)
- MET-ASN--LEU-ALA-PHE-PRO-ARG-MET (MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE)
- SCPB
Cardioactive Peptide B (sMall)
- MNYLAFPRM-NH2
- SCPB
- SMALL CARDIOACTIVE PEPTIDE B
- CARDIOACTIVE PEPTIDE B (SMALL)
- H-MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
- MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET-NH2
- MET-ASN-TYR-LEU-ALA-PHE-PRO-ARG-MET AMIDE