羟基匹格列酮
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- CAS号:
- 146062-44-4
- 英文名:
- Hydroxypioglitazone
- 英文别名:
- Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV) ;Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
- 中文名:
- 羟基匹格列酮
- 中文别名:
- 羟基吡格列酮;羟基匹格列酮;吡格列酮14;羟基吡格列酮M4;吡格列酮M4代谢物;羟基吡格列酮-D4;羟基匹格列酮M-IV;羟基吡格列酮M-IV;羟基匹格列酮溶液, 100PPM
- CBNumber:
- CB1299313
- 分子式:
- C19H20N2O4S
- 分子量:
- 372.44
- MOL File:
- 146062-44-4.mol
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羟基匹格列酮化学性质
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熔点:
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157-1580C
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沸点:
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627.6±55.0 °C(Predicted)
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密度:
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1.325±0.06 g/cm3(Predicted)
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储存条件:
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-20°C Freezer, Under Inert Atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly, Sonicated)
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酸度系数(pKa):
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6.35±0.50(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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稳定性:
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Hygroscopic
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CAS 数据库:
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146062-44-4
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羟基匹格列酮性质、用途与生产工艺
Leriglitazone (Hydroxypioglitazone)，吡格列酮的代谢产物。
Leriglitazone (Hydroxypioglitazone) 是 PPARγ 激动剂，通过稳定 PPARγ (AF-2) 共激活剂结合表面和增强共激活剂结合能力，提供高转录效力。
Leriglitazone（Hydroxypioglitazone) 与 PPARγC (LBD) 结合，其 Ki 值为 1.2 μM，诱导 PPARγ (LBD) 转录效率，EC50 为 680 nM。
Ki: 1.2 μM (PPARγ LBD); EC: 680 nM (PPARγ LBD) (Leriglitazone)
羟基匹格列酮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/16 | HY-117727 | Leriglitazone | | 1 mg | 2480元 |
| 2024/01/16 | HY-117727 | 羟基匹格列酮
Leriglitazone | 146062-44-4 | 5mg | 6200元 |
羟基匹格列酮
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146062-44-4, 羟基匹格列酮 相关搜索:
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Various Metabolites and Impurities
- Sulfur & Selenium Compounds
- 标准品
- 羟基吡格列酮M4
- 吡格列酮14
- 羟基匹格列酮溶液, 100PPM
- 吡格列酮M4代谢物
- 羟基吡格列酮-D4
- 羟基匹格列酮M-IV
- 羟基吡格列酮M-IV
- 羟基吡格列酮
- 羟基匹格列酮
- 146062-44-4
- Hydroxypioglitazone M4
- 2,4-Thiazolidinedione, 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-
- Pioglitazone Impurity 4
- Leriglitazone
- Pioglitazone M4 Metabolite
- Hydroxy Pioglitazone Solution, 100ppm
- Pioglitazone Impurity 18
- Pioglitazone, hydroxy M-IV
- 5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
- Hydroxy Pioglitazone (M-IV)
- HYDROXYPIOGLITAZONE