黑色素聚集激素肽
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- CAS号:
- 87218-84-6
- 英文名:
- MELANIN CONCENTRATING HORMONE, SALMON
- 英文别名:
- MCH (SALMON);MELANIN CONCENTRATING HORMONE;Salmon melanin-concentrating hormone;MELANIN CONCENTRATING HORMONE, SALMON;Melanin concentrating hormone salmon, ≥90%;MCH (salMon)
Melanin-Concentrating HorMone (salMon);Melanin-concentratinghormone (Oncorhynchus keta) (9CI);ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL;Asp-Thr-Met-Arg-c[Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys]-Trp-Glu-Val;H-ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL-OH
- 中文名:
- 黑色素聚集激素肽
- 中文别名:
- 黑素浓集素;黑色素聚集激素肽;鲑鱼黑色素聚集激素;黑色素聚集激酶素(MCH
- CBNumber:
- CB1314540
- 分子式:
- C89H139N27O24S4
- 分子量:
- 2099.5
- MOL File:
- 87218-84-6.mol
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黑色素聚集激素肽化学性质
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密度:
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1.52±0.1 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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形态:
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Solid
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黑色素聚集激素肽性质、用途与生产工艺
Melanin Concentrating Hormone, salmon是最初在硬骨鱼的垂体中发现的19个氨基酸组成的神经肽，它调节食物摄入，能量平衡，睡眠状态和心血管系统。 Melanin-concentrating hormone是 SLC-1/GPR24 和 MCHR2 的配体。
An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein.
Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice.
黑色素聚集激素肽
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87218-84-6, 黑色素聚集激素肽 相关搜索:
- Obesity Research
- Neuropeptides
- Hormones
- Peptide
- 多肽
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- 目录多肽
- 标准品
- 细胞生物学
- Cell Signaling and Neuroscience
- Cell Biology
- BioChemical
- Obesity Research
- Neuropeptides
- Hormones
- Cytokines, Growth Factors and Hormones
- C89H139N27O24S4
- 黑素浓集素
- 黑色素聚集激素肽
- 鲑鱼黑色素聚集激素
- 黑色素聚集激酶素(MCH
- 87218-84-6
- Melanin-concentratinghormone (Oncorhynchus keta) (9CI)
- L-Valine, L-α-aspartyl-L-threonyl-L-methionyl-L-arginyl-L-cysteinyl-L-methionyl-L-valylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-arginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-α-glutamyl-, cyclic (5→14)-disulfide
- Melanin concentrating hormone salmon, ≥90%
- Salmon melanin-concentrating hormone
- MCH (salMon)
Melanin-Concentrating HorMone (salMon)
- REF DUPL: Asp-Thr-Met-Arg-c[Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys]-Trp-Glu-Val
- Asp-Thr-Met-Arg-c[Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys]-Trp-Glu-Val
- ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL: DTMRCMVGRVYRPCWEV DISULFIDE BRIDGE CYS5-CYS14
- H-ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL-OH
- ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL [DISULFIDE BRIDGE: 5-14]
- ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL
- MCH (SALMON)
- MELANIN CONCENTRATING HORMONE, SALMON
- MELANIN CONCENTRATING HORMONE