己曲安奈德
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- CAS号:
- 5611-51-8
- 英文名:
- Triamcinolone hexacetonide
- 英文别名:
- tatba;C08185;cl34433;lederspan;aristospan;Triamcinolone hexatonide;TRIAMCINOLONE HEXACETONIDE;TRIAMCINOLONEHEXACETONIDE,USP;Triamcinolone hexacetonide CRS;Triamcinolone Hexacetonide (200 mg)
- 中文名:
- 己曲安奈德
- 中文别名:
- 己曲安奈德;曲安西龙叔丁乙酸酯;己曲安西龙 标准品;化合物 T17162;己曲安奈德 EP标准品;己曲安奈德 USP标准品;己曲安奈德(16,17-异丙烯二酮-D6,98%)
- CBNumber:
- CB1434277
- 分子式:
- C30H41FO7
- 分子量:
- 532.64
- MOL File:
- 5611-51-8.mol
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己曲安奈德化学性质
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熔点:
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295-296° (dec); mp 271-272° (dec)
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比旋光度:
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D25 +90±2° (c = 1.13% in chloroform)
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沸点:
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619.5±55.0 °C(Predicted)
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密度:
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1.1277 (estimate)
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储存条件:
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2-8°C
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溶解度:
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Practically insoluble in water, sparingly soluble in anhydrous ethanol and in methanol.
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酸度系数(pKa):
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13.09±0.70(Predicted)
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颜色:
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Fine, white, needle-like crystals
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EPA化学物质信息:
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Triamcinolone hexacetonide (5611-51-8)
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己曲安奈德性质、用途与生产工艺
Triamcinolone hexacetonide 是一种常用的长效类固醇，有潜力用于亚急性和慢性炎性关节疾病的研究。
Triamcinolone hexacetonide produces a marked, dose-dependent protective effect in the model of chemically induced articular cartilage damage. Guinea pig injected with Triamcinolone hexacetonide shows much less prominent fibrillation and osteophytes. Cell loss is less extensive. A single injection of Triamcinolone hexacetonide into the ipsilateral knee of rabbits which have been subjected to partial lateral meniscectomy and transection of the sesamoid and collateral fibular ligaments reduces chondrocyte cloning, loss of cells, osteophyte formation, and fibrillation. The half-life of commercially available Triamcinolone hexacetonide in the vitreous is double that of Triamcinolone hexacetonide, but the former is toxic to the retina in this rabbit model. Reformulated iso-osmolar Triamcinolone hexacetonide shows no evidence of deleterious effects to retina function or structure. Local application of Triamcinolone hexacetonide at a site of lingual nerve injury leads to changes that are potentially beneficial such as reduced mechanical sensitivity and enhanced regeneration.
类别
有毒物品
可燃性危险特性
可燃; 燃烧产生有毒氟化物烟雾
储运特性
库房通风低温干燥
灭火剂
干粉,泡沫,沙土,二氧化碳, 雾状水
己曲安奈德
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-U00103 | Triamcinolone hexacetonide | | 1 mg | 1363元 |
| 2024/01/25 | HY-U00103 | 己曲安奈德
Triamcinolone hexacetonide | 5611-51-8 | 5 mg | 3000元 |
己曲安奈德
生产厂家
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己曲安奈德国内生产厂家
5611-51-8, 己曲安奈德 相关搜索:
- Steroid and Hormone
- 化学试剂
- 医药原料药
- C30H41FO7
- 己曲安奈德 EP标准品
- 己曲安西龙 标准品
- 己曲安奈德 USP标准品
- 己曲安奈德(16,17-异丙烯二酮-D6,98%)
- 化合物 T17162
- 己曲安奈德
- 曲安西龙叔丁乙酸酯
- 5611-51-8
- Triamcinolone Hexacetonide (1679008)
- Pregna-1,4-diene-3,20-dione, 21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-
- Triamcinolone hexacetonide CRS
- lederspan
- cl34433
- aristospan
- 4-diene-3,20-dione,9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-pregna-cyc
- (11β,16α)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- Triamcinolone Hexacetonide (200 mg)
- C08185
- 9-Fluoro-11β,21-dihydroxy-16α,17-(isopropylidenebisoxy)pregna-1,4-diene-3,20-dione 21-(3,3-dimethylbutyrate)
- 21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11β-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- TRIAMCINOLONEHEXACETONIDE,USP
- Triamcinolone hexatonide
- TRIAMCINOLONE HEXACETONIDE
- tatba
- lic16,17-acetalwithacetone,21-(3,3-dimethylbutyrate)