L-抗坏血酸-2-单磷酸酯三环己铵盐
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- CAS号:
- 23313-12-4
- 英文名:
- L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT
- 英文别名:
- Vitamin C phosphate;Ascorbyl-2-phosphate;ascorbate-2-phosphate;Ascorbyl monophosphate;Ascorbyl-2-monophosphate;Ascorbic Acid Impurity 6;2-Phospho-L-ascorbic acid;MIJPAVRNWPDMOR-ZAFYKAAXSA-N;L-Ascorbic acid, 2-(dihydrogen phosphate);LAscorbic acid 2phosphate,L Ascorbic acid 2 phosphate
- 中文名:
- L-抗坏血酸-2-单磷酸酯三环己铵盐
- 中文别名:
- 2-磷酸抗坏血酸;化合物 T19390;L-抗坏血酸-2-单磷酸酯三环己铵盐;维生素C磷酸酯(L-抗坏血酸-2-磷酸酯)
- CBNumber:
- CB1505885
- 分子式:
- C6H9O9P
- 分子量:
- 256.1
- MOL File:
- 23313-12-4.mol
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L-抗坏血酸-2-单磷酸酯三环己铵盐化学性质
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沸点:
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682.7±65.0 °C(Predicted)
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密度:
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2.01±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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1.38±0.10(Predicted)
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L-抗坏血酸-2-单磷酸酯三环己铵盐性质、用途与生产工艺
L-ascorbic acid 2-phosphate 是一种长效的维生素 C 衍生物 (vitamin C derivative)，可以刺激胶原蛋白的表达和形成。L-ascorbic acid 2-phosphate 可以作为培养基补充人脂肪干细胞 (hASCs) 的成骨分化。L-ascorbic acid 2-phosphate 增加成骨细胞分化过程中 hASC 中的碱性磷酸酶 (ALP) 活性和 runx2A 的表达。
IC50: alkaline phosphatase (ALP); collagen formation; runx2A
L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect .
L-Ascorbic acid 2-phosphate (50 µM-250 µM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex.
Cell Proliferation Assay
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Cell Line:
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Human corneal endothelial cells (HCECs)
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Concentration:
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0.1 mM; 0.3 mM; 1.5 mM
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Incubation Time:
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2 to 3 weeks with medium exchange every 2 to 3 days
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Result:
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Stimulated HCEC cells growth.
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L-抗坏血酸-2-单磷酸酯三环己铵盐
上下游产品信息
上游原料
下游产品
23313-12-4, L-抗坏血酸-2-单磷酸酯三环己铵盐 相关搜索:
- 有机产品
- 维生素C 系列
- 食品添加剂
- 有机化工原料
- 中间体
- C24H48N3O9P
- 2-磷酸抗坏血酸
- 化合物 T19390
- 维生素C磷酸酯(L-抗坏血酸-2-磷酸酯)
- L-抗坏血酸-2-单磷酸酯三环己铵盐
- 23313-12-4
- LAscorbic acid 2phosphate,L Ascorbic acid 2 phosphate
- 2-Phospho-L-ascorbic acid
- MIJPAVRNWPDMOR-ZAFYKAAXSA-N
- Ascorbic Acid Impurity 6
- [2-(1,2-dihydroxyethyl)-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate
- L-Ascorbic acid, 2-(dihydrogen phosphate)
- Ascorbyl-2-phosphate
- Ascorbyl-2-monophosphate
- Ascorbyl monophosphate
- ascorbate-2-phosphate
- l-ascorbic acid 2-monophosphate tris-cyclohexylammonium salt
- Vitamin C phosphate