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格隆溴铵中间体

CAS号: 13118-10-0
英文名称: 1-Methyl-3-(a-cyclopentylmandeloyloxy)pyrrolidinehydrochloride
英文同义词: Ahr-376;Ahr 376;Glycopyrrolate Intermediate;1-Methyl-3-(a-cyclopentylmandeloyloxy)pyrrolidinehydrochloride;3-Pyrrolidinol, 1-methyl-, .alpha.-cyclopentylmandelate, hydrochloride;1-Methyl-3-pyrrolidyl .alpha.-phenylcyclopentylmandelate hydrochloride;1-Methyl-3-pyrrolidyl .alpha.-phenylcyclopentylglycolate hydrochloride;1-Methyl-3-pyrrolidinyl .alpha.-cyclopentylmandelic acid hydrochloride;Mandelic acid, .alpha.-cyclopentyl-, 1-methyl-3-pyrrolidinyl, hydrochloride;1-Methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate hydrochloride
中文名称: 格隆溴铵中间体
中文同义词: 1-甲基-3-(Α-环戊基扁桃酰氧基)吡咯烷盐酸盐;1-甲基-3-(A-环戊基扁桃酰氧基)吡咯烷盐酸盐
CBNumber: CB21450767
分子式:
分子量: 0
MOL File: 13118-10-0.mol
格隆溴铵中间体化学性质
安全信息
海关编码 : 2917394000

格隆溴铵中间体 性质、用途与生产工艺

用途 
胃长宁的中间体。
生产方法 
用苯乙烯以高锰酸钾氧化,生成苯乙酮酸,然后与甲醇在硫酸参与下酯化得苯乙酮酸甲酯,将后者与环戊二烯加成(格氏反应,先以金属镁、无水乙醚、溴乙烷制成格氏试剂),得α-环戊二烯基扁桃酸甲酯,进而在活性镍作用下加压催化氢化,最后与N-甲基吡咯烷-3-醇酯交换制得该品。
类别
有毒物品
毒性分级
高毒
急性毒性
口服-小鼠 LD50:500 毫克/公斤; 腹腔-小鼠LD50: 250 毫克/公斤
可燃性危险特性
可燃; 燃烧释放有毒氮氧化物和氯化氢烟雾
储运特性
库房通风低温干燥; 与食品原料分开存放
灭火剂
干粉、泡沫、砂土、二氧化碳, 雾状水
格隆溴铵中间体 上下游产品信息
上游原料
1-甲基吡咯烷 苯甲酰甲酸 格氏试剂 苯乙烯 乙醚 高锰酸钾 溴乙烷 苯甲酰甲酸甲酯 环戊二烯
下游产品
格隆溴铵中间体 生产厂家      全球有 3家供应商        格隆溴铵中间体国内生产厂家
供应商联系电话传真电子邮件国家产品数优势度
Alchem Pharmtech,Inc. 8485655694 sales@alchempharmtech.com美国 63729 58
苏州旺山旺水生物医药有限公司 13776074850 qq 246911538113776074850 qq 2469115381sales@vigonvita.cn中国 112 58
 
13118-10-0, 格隆溴铵中间体 相关搜索:
3-羟基-1-甲基四氢吡咯 格隆溴铵 N-甲基-3-吡咯烷基 环戊基扁桃酸酯 2-环戊基-2-羟基苯乙酸 Α-苯基环戊基乙酸 2-环戊基-2-羟基苯乙酸甲酯
1-甲基-3-(Α-环戊基扁桃酰氧基)吡咯烷盐酸盐 1-甲基-3-(A-环戊基扁桃酰氧基)吡咯烷盐酸盐 13118-10-0 mandelic acid, alpha-cyclopentyl-, 1-methyl-3-pyrrolidinyl ester, hydrochloride 1-methyl-3-pyrrolidyl alpha-phenylcyclopentaneglycolate hydrochloride ahr 376 alpha-cyclopentylmandelic acid 1-methyl-3-pyrrolidinyl ester hydrochloride mandelic acid, alpha-cyclopentyl-,1-methyl-3-pyrrolidinyl ester, hydrochloride 1-Methyl-3-(-cyclopentylmandeloyloxy)pyrrolidine hydrochloride 1-Methyl-3-pyrrolidinyl -cyclopentylmandelate hydrochloride 1-Methyl-3-(a-cyclopentylmandeloyloxy)pyrrolidinehydrochloride Glycopyrrolate Intermediate 1-Methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate hydrochloride Mandelic acid, .alpha.-cyclopentyl-, 1-methyl-3-pyrrolidinyl, hydrochloride Mandelic acid, .alpha.-cyclopentyl-, 1-methyl-3-pyrrolidinyl ester, hydrochloride Benzeneacetic acid, .alpha.-cyclopentyl-.alpha.-hydroxy-, 1-methyl-3-pyrrolidinyl ester, hydrochloride Ahr-376 Ahr 376 3-Pyrrolidinol, 1-methyl-, .alpha.-cyclopentylmandelate, hydrochloride 1-Methyl-3-pyrrolidyl .alpha.-phenylcyclopentylmandelate hydrochloride 1-Methyl-3-pyrrolidyl .alpha.-phenylcyclopentylglycolate hydrochloride 1-Methyl-3-pyrrolidinyl .alpha.-cyclopentylmandelic acid hydrochloride
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