154355-75-6
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- CAS号:
- 154355-75-6
- 英文名:
- ATRELEUTON
- 英文别名:
- ATRELEUTON;COX/5-LO-IN-1;Atreleuton analog;COX/5LOIN1,COX/5 LO IN 1;Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-
- 中文名:
- 154355-75-6
- 中文别名:
- 化合物 T13263
- CBNumber:
- CB22446514
- 分子式:
- C16H15FN2O2S
- 分子量:
- 318.37
- MOL File:
- 154355-75-6.mol
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154355-75-6化学性质
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沸点:
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506.7±60.0 °C(Predicted)
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密度:
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1.37±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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9.63±0.50(Predicted)
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154355-75-6性质、用途与生产工艺
COX/5-LO-IN-1 (Atreleuton analog) 是 cylooxygenase 和 5-lipoxygenase (5-LO) 的抑制剂，用于炎症性和过敏性疾病的研究。
COX/5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4, and E4 and cyclooxygenase products such as prostaglandins and thromboxane and are useful in the treatment of inflammatory and allergic disease states. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase, with IC
50
of 0.2 μM in human whole blood.
154355-75-6
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-117853 | Atreleuton | | 5 mg | 2830元 |
154355-75-6, 154355-75-6 相关搜索:
- 抑制剂
- 化合物 T13263
- 154355-75-6
- COX/5LOIN1,COX/5 LO IN 1
- Atreleuton analog
- COX/5-LO-IN-1
- Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-
- ATRELEUTON