OAC2
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- CAS号:
- 6019-39-2
- 英文名:
- 5-benzoylaminoindole
- 英文别名:
- OAC2;CS-2128;OAC2?, >98%;OAC-2;OAC 2;5-benzoylaminoindole;N-(1H-Indol-5-yl)benzaMide;Benzamide, N-1H-indol-5-yl-
- 中文名:
- OAC2
- 中文别名:
- 优选]OAC2;化合物OAC2;OAC-2,OCT4激活剂;N-(1H-吲哚-5-基)苯甲酰胺;N-(1H-吲哚-5-基)苯甲酰胺, >98%
- CBNumber:
- CB22523495
- 分子式:
- C15H12N2O
- 分子量:
- 236.27
- MOL File:
- 6019-39-2.mol
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OAC2化学性质
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熔点:
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165 - 167°C
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沸点:
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364.3±15.0 °C(Predicted)
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密度:
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1.307±0.06 g/cm3(Predicted)
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储存条件:
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Sealed in dry,Room Temperature
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溶解度:
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DMSO (Slightly), Methanol (Slightly)
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酸度系数(pKa):
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13.99±0.43(Predicted)
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形态:
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Solid
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颜色:
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Pale Yellow
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OAC2性质、用途与生产工艺
OAC-2是transcription factor 4 (OCT4)的激活剂,增强iPSC重编程效率。
Octamer-binding transcription factor 4 (Oct4) is a master regulator of the induction and maintenance of cellular pluripotency, and has crucial roles in early stages of differentiation. It is the only factor that cannot be substituted by other members of the same protein family to induce pluripotency. Oct4 has been shown to be an essential regulator of embryonic stem cell (ESC) pluripotency and key to the reprogramming process. OAC2 is a structural analog of OAC1. OAC2 activates both Oct4 and Nanog reporters to a similar extent as OAC1. OAC1 and its two structural analogs OAC2 and OAC3 enhances reprogramming efficiency fourfold, up to as high as 2.75%, and accelerates the appearance of iPSC colonies 3 to 4 d when used in combination with the four reprogramming factors, Oct4, Sox2, Klf4, and c-Myc.
OAC2
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-12884 | OAC2 | | 5 mg | 375元 |
2024/08/19 | HY-12884 | OAC2 OAC2 | 6019-39-2 | 10mg | 600元 |
OAC2
生产厂家
全球有 86家供应商
OAC2国内生产厂家
6019-39-2, OAC2 相关搜索:
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- Inhibitors
- 药靶配体
- 小分子抑制剂,天然产物
- 小分子抑制剂
- OAC-2,OCT4激活剂
- 优选]OAC2
- 化合物OAC2
- N-(1H-吲哚-5-基)苯甲酰胺
- N-(1H-吲哚-5-基)苯甲酰胺, >98%
- 6019-39-2
- Benzamide, N-1H-indol-5-yl-
- OAC2?, >98%
- OAC-2;OAC 2
- CS-2128
- OAC2
- N-(1H-Indol-5-yl)benzaMide
- 5-benzoylaminoindole