网站主页 >> CAS数据库列表 >> (S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
(S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
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- CAS号:
- 1515856-92-4
- 英文名:
- XEN445
- 英文别名:
- XEN445;CS-1251;XEN 445, >=98%;XEN 445; XEN-445;XEN445 >=98% (HPLC);Inhibitor,inhibit,XEN445;(S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid;2-[(3S)-3-(2-Pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)benzoic acid;2-[(3S)-3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acid;Benzoic acid, 2-[(3S)-3-(2-pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)-
- 中文名:
- (S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
- 中文别名:
- 化合物XEN445;XEN445,内皮脂肪酶抑制剂;(S)-2-(3-(吡啶-2-基甲氧基)吡咯烷-1-基)-5-(三氟甲基)苯甲酸;2-[(3S)-3-(2-吡啶基甲氧基)-1-吡咯烷基]-5-(三氟甲基)苯甲酸
- CBNumber:
- CB22715681
- 分子式:
- C18H17F3N2O3
- 分子量:
- 366.33
- MOL File:
- 1515856-92-4.mol
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(S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL化学性质
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沸点:
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490.9±45.0 °C(Predicted)
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密度:
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1.40±0.1 g/cm3(Predicted)
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储存条件:
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under inert gas (nitrogen or Argon) at 2-8°C
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溶解度:
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DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 14 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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3.35±0.36(Predicted)
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(S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL性质、用途与生产工艺
XEN445是内皮脂肪酶(EL)抑制剂，IC50为0.237 uM，具有很好的ADME和PK活性，能提高小鼠血浆中高密度脂蛋白胆固醇浓度。
(S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-12246 | XEN445 | | 1 mg | 266元 |
| 2024/01/25 | HY-12246 | (S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
XEN445 | 1515856-92-4 | 5mg | 700元 |
(S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
生产厂家
1515856-92-4, (S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL 相关搜索:
XE991dihydrochloride (S)-(+)-2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂卓-6-基)乙酸叔丁酯 (S)-(4-氟苯基)-{3-[3-(4-氟苯基)-[1,2,4]二唑-5-基]哌啶-1-基}甲酮 (S)-1-[4-[[2-(2-氨基嘧啶-5-基)-7-甲基-4-(吗啉-4-基)噻吩并[3,2-D]嘧啶-6-基]甲基]哌嗪-1-基]-2-羟基丙-1-酮
- Inhibitors
- 药靶配体
- 小分子抑制剂，天然产物
- 小分子抑制剂
- XEN445,内皮脂肪酶抑制剂
- 化合物XEN445
- (S)-2-(3-(吡啶-2-基甲氧基)吡咯烷-1-基)-5-(三氟甲基)苯甲酸
- 2-[(3S)-3-(2-吡啶基甲氧基)-1-吡咯烷基]-5-(三氟甲基)苯甲酸
- 1515856-92-4
- Inhibitor,inhibit,XEN445
- XEN445 >=98% (HPLC)
- Benzoic acid, 2-[(3S)-3-(2-pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)-
- XEN 445; XEN-445
- CS-1251
- 2-[(3S)-3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl]-5-(trifluoromethyl)benzoic acid
- 2-[(3S)-3-(2-Pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)benzoic acid
- (S)-2-(3-(PYRIDIN-2-YLMETHOXY)PYRROLIDIN-1-YL)-5-(TRIFLUOROMETHYL)BENZOIC ACID. HCL
- XEN445
- 2-[(3S)-3-(2-Pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)benzoic acid XEN445
- (S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid
- XEN445 2-[(3S)-3-(2-Pyridinylmethoxy)-1-pyrrolidinyl]-5-(trifluoromethyl)benzoic acid
- XEN 445, >=98%