6-羟基多巴胺氢溴酸盐

6-羟基多巴胺氢溴酸盐性质、用途与生产工艺

概述

6-羟基多巴胺氢溴酸盐又叫6-OHDA，是儿茶酚的羟基化衍生物，是一种有效导致多巴胺神经元变性的神经毒剂。

用途

6-羟基多巴胺氢溴酸盐是用来制作帕金森病动物模型的第一种药物，最常用的方法是单侧注射6-羟基多巴胺氢溴酸盐至黑质或者中央前脑束，这可以使DA神经元细胞在较短的时程内快速的死亡，这与急性MPTP模型相似。

生物活性

Oxidopamine hydrobromide (6-OHDA hydrobromide) 是神经递质多巴胺 (neurotransmitter dopamine) 拮抗剂，是一种广泛使用的神经毒素，可选择性地破坏多巴胺能神经元。

用途 

生化试剂，可诱发帕金森病大鼠模型。

6-羟基多巴胺氢溴酸盐 上下游产品信息

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6-羟基多巴胺氢溴酸盐 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/01/16	S5324	6-羟基多巴胺氢溴酸盐 Oxidopamine (hydrobromide)	636-00-0	25mg	1041.11元
2024/01/16	S5324	6-羟基多巴胺氢溴酸盐 Oxidopamine (hydrobromide)	636-00-0	100mg	3030.67元

6-羟基多巴胺氢溴酸盐 生产厂家

 

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