5-O-去甲基奥美拉唑
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- CAS号:
- 151602-49-2
- 英文名:
- 5-O-DESMETHYL OMEPRAZOLE
- 英文别名:
- 5-Desmethylomeprazole;Omeprazole Impurity L;5-o-demethylomeprazole;Esomeprazol impurity L;Esomeprazole impurity M;5-O-DESMETHYL OMEPRAZOLE;EsoMeprazole sodiuM iMpurity L;5-O-Desmethyl Omeprazole Metabolite;Omeprazole Impurity L(5-O-Desmethyl Omeprazole);5-O-Desmethyl Omeprazole Discontinued see product # D292120
- 中文名:
- 5-O-去甲基奥美拉唑
- 中文别名:
- 奥美拉唑杂质L;埃索美拉唑杂质L;5-氧去甲基奥美拉唑;5-O-脱甲基奥美拉唑;5-O-去甲基奥美拉唑;5‘-脱甲氧基奥美拉唑;奥美拉唑杂质L(5-O-地甲基奥美拉唑);2-((((4-甲氧基-3,5-二甲基吡啶-2-基)甲基)亚磺酰基)-1H-苯并[D]咪唑-5-醇(奥美拉唑杂质)
- CBNumber:
- CB2306821
- 分子式:
- C16H17N3O3S
- 分子量:
- 331.39
- MOL File:
- 151602-49-2.mol
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5-O-去甲基奥美拉唑化学性质
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熔点:
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238-240°C
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沸点:
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630.5±65.0 °C(Predicted)
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密度:
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1.46±0.1 g/cm3(Predicted)
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储存条件:
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-20°C Freezer
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溶解度:
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Dimethylformamide, Dimethyl Sulfoxide, Ethanol, Methanol
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酸度系数(pKa):
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8.71±0.10(Predicted)
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形态:
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Solid
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颜色:
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Light-Yellow
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CAS 数据库:
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151602-49-2
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5-O-去甲基奥美拉唑性质、用途与生产工艺
该药属胃质子泵抑制药，奥美拉唑口服后，可浓集于壁细胞分泌小管周围，转变为次磺酰胺衍生物。其硫原子与H+，K+-ATP酶上的巯基结合，使H+泵失活，减少胃酸分泌。本药还能增加胃黏膜血流量，有利于溃疡病的治疗。主要用于胃、十二指肠溃疡，反流性食管炎和卓艾综合征，对H2受体阻断药疗效不佳的患者也有效，该药与某些抗菌药合用可治疗幽门螺杆菌感染。5-O-去甲基奥美拉唑为奥美拉唑杂质。
5-O-去甲基奥美拉唑
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151602-49-2, 5-O-去甲基奥美拉唑 相关搜索:
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Various Metabolites and Impurities
- Metabolite Reference Standard
- 杂质对照品
- 杂质标准品
- 1151602-49-2
- 奥美拉唑杂质L(5-O-地甲基奥美拉唑)
- 2-((((4-甲氧基-3,5-二甲基吡啶-2-基)甲基)亚磺酰基)-1H-苯并[D]咪唑-5-醇(奥美拉唑杂质)
- 5-氧去甲基奥美拉唑
- 奥美拉唑杂质L
- 5-O-脱甲基奥美拉唑
- 5-O-去甲基奥美拉唑
- 埃索美拉唑杂质L
- 5‘-脱甲氧基奥美拉唑
- 151602-49-2
- Omeprazole Impurity L(5-O-Desmethyl Omeprazole)
- 2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-5-ol? (Omeprazole Impurity）
- 5-O-Desmethyl Omeprazole Metabolite
- Esomeprazol impurity L
- 2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazol-5-ol
- Omeprazole Impurity L
- 5-o-demethylomeprazole
- 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-3H-benzimidazol-5-ol
- 5-O-DESMETHYL OMEPRAZOLE
- 4-Methoxy-2-[[(RS)-(5-hydroxy -1H-benziMidazol-2-yl)sulfinyl]Methyl]-3,5-diMethylpyridine
- EsoMeprazole sodiuM iMpurity L
- 1H-Benzimidazol-6-ol,2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
- Esomeprazole impurity M
- 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol
- 5-O-Desmethyl Omeprazole Discontinued see product # D292120
- 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-5-ol
- 5-Desmethylomeprazole