2,4,6-三羟基苯乙酮
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- CAS号:
- 480-66-0
- 英文名:
- 2',4',6'-Trihydroxyacetophenone monohydrate
- 英文别名:
- THAP;Phloracetophenone;PHLOROACETOPHENONE;Monoacetylphloroglucinol;2-Acetylphloroglucinol hydrate;2',4',6'-TRIHYDROXYACETOPHENONE;2,4,6-trihydroxylacetophenone monohydrate;NSC 54927;Phloracetophene;Acetophloroglucine
- 中文名:
- 2,4,6-三羟基苯乙酮
- 中文别名:
- 一乙酰间苯三酚;2-乙酰间苯三酚;6-三羟基苯乙酮;三羟基苯乙酮一水合物;2,4,6-三羟基苯乙酮;2,4,6-三羟基苯乙酮，水合;2,4,6-三羟基苯乙酮 一水;2,4,6-三羟基苯乙酮无水物;2',4',6'-三羟基苯乙酮;1-(2,4,6-三羟苯基)乙酮
- CBNumber:
- CB2333652
- 分子式:
- C8H8O4
- 分子量:
- 168.15
- MOL File:
- 480-66-0.mol
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2,4,6-三羟基苯乙酮化学性质
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熔点:
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219-221 °C(lit.)
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沸点:
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257.07°C (rough estimate)
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密度:
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1.3037 (rough estimate)
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折射率:
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1.5090 (estimate)
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储存条件:
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Store below +30°C.
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溶解度:
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DMSO (Sparingly), Ethanol (Slightly), Methanol (Slightly), Water (Very Slightly,
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形态:
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Powder
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酸度系数(pKa):
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7.76±0.23(Predicted)
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颜色:
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light yellow
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水溶解性:
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Soluble in water.
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BRN:
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1911197
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稳定性:
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Stable under recommended storage conditions., Stable Under Recommended Storage C
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LogP:
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1.472 (est)
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CAS 数据库:
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480-66-0(CAS DataBase Reference)
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NIST化学物质信息:
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Ethanone, 1-(2,4,6-trihydroxyphenyl)-(480-66-0)
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EPA化学物质信息:
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Ethanone, 1-(2,4,6-trihydroxyphenyl)- (480-66-0)
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2,4,6-三羟基苯乙酮性质、用途与生产工艺
Phloracetophenone (2,4,6-trihydroxyacetophenone) 是多叶姜黄 (Curcuma comosa Roxb) 中苯乙酮糖苷的糖苷配基部分，具有降低胆固醇作用，能够增强胆固醇 7α-羟化酶 (CYP7A1) 的活性；Phloracetophenone 通过 Mrp2 刺激胆汁分泌。
Cholesterol 7α-hydroxylase, Mrp2
Phloracetophenone (2,4,6-trihydroxyacetophenone) is a cholesterol-lowering agent, enhances cholesterol 7α-hydroxylase (CYP7A1) activity, and elevates CYP7A1 mRNA level.
Phloracetophenone (1, 2, and 4 μmol/min) immediately and dose-dependently increases bile acid-independent bile flow in the isolated perfused rat liver.
Phloracetophenone (2,4,6-trihydroxyacetophenone; 125 or 250 μmol/kg, intraduodenal injection) shows choleretic activity requiring multidrug resistance protein-2 (Mrp2) in rats. Phloracetophenone (40 μmol/min) partially prevents the E2-17G induced cholestasis.
化学性质
微黄色结晶。熔点217-219℃。
用途
本品用于有机合成、医药中间体和合成新型抗氧剂黄烷酮等。
2,4,6-三羟基苯乙酮
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-W008226 | Phloracetophenone | | 500 mg | 100元 |
| 2024/01/25 | HY-W008226 | 2,4,6-三羟基苯乙酮
Phloracetophenone | 480-66-0 | 10mM * 1mLin DMSO | 110元 |
2,4,6-三羟基苯乙酮
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2,4,6-三羟基苯乙酮国内生产厂家
480-66-0, 2,4,6-三羟基苯乙酮 相关搜索:
- Matrix Materials (MALDI-TOF-MS)
- Mass Spectrometry
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Aromatics
- Organic Building Blocks
- Ketones
- Chemical Synthesis
- C7 to C8
- Building Blocks
- Inhibitors
- Analytical Chemistry
- Carbonyl Compounds
- Alcohols and Derivatives
- Aromatic Acetophenones & Derivatives (substituted)
- 药靶配体
- 有机类
- 有机产品
- 中间体产品
- 化工
- 对照品
- 有机原料
- 化学试剂
- 中间体-有机中间体
- 合成材料中间体
- 化工原料
- 医药原料
- 其它酚类
- 活性分子
- 有机化工原料
- 羰基化合物
- 醇类及衍生物
- 小分子抑制剂，天然产物
- 小分子抑制剂
- 酮
- 其它有机金属化合物
- 中间体
- 有机砌块
- 医药中间体
- 通用试剂
- 微生物代谢物
- Organic Building Blocks
- Carbonyl Compounds
- Analytical Chromatography Product Catalog
- Analytical Reagents
- Building Blocks
- C7 to C8
- Ketones
- HO3C6H2COCH3H2O
- C8H8O4xH2O
- 2',4',6'-三羟基苯乙酮
- 1-(2,4,6-三羟基苯基)乙烷-1-酮
- 2',4',6'-三羟基乙酰苯一水化物
- 2,4,6-三羟基苯乙酮无水物
- 相关水合物CAS号:249278-28-2
- 2,4,6-三羟基苯乙酮 一水
- 6-三羟基苯乙酮
- 2,4,6-三羟基苯乙酮(淡黄色粉末)