食欲肽B (人)
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- CAS号:
- 205640-91-1
- 英文名:
- OREXIN B (HUMAN)
- 英文别名:
- HYPOCRETIN-2;Human orexin B;OREXIN B (HUMAN);HYPOCRETIN-2, HUMAN;OREXIN B HUMAN ≥98%;PubChem ID: 90479794;OREXINS OREXIN B HUMAN;OREXIN B (HUMAN) USP/EP/BP;Orexin B (human), ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
- 中文名:
- 食欲肽B (人)
- 中文别名:
- 食欲肽B (人);人OREXIN B;食欲肽B(人) ≥98%;食欲素B(人类)三氟乙酸盐;食欲肽B(人) ≥98%, ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 (TRIFLUOROACETATE SALT)
- CBNumber:
- CB2384164
- 分子式:
- C123H212N44O35S
- 分子量:
- 2899.34
- MOL File:
- 205640-91-1.mol
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食欲肽B (人)化学性质
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密度:
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1.49±0.1 g/cm3(Predicted)
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储存条件:
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-20°C
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水溶解性:
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Soluble to 1 mg/ml in Water
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序列:
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H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
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食欲肽B (人)性质、用途与生产工艺
Orexin B, human是 Orexin 受体的内源性激动剂，与OX1和OX2结合的 Ki 值分别为 420 和 36 nM。
Ki: 420 nM (OX1), 36 nM (OX2)
Orexin B is derived by proteolytic amino acid precursor, prepro-orexin, which is encoded by a gene localized to chromosome 17q21 in humans. In radioligand binding studies, Orexin B has a higher affinity for the OX2 receptor. Human Orexin B has two amino acid substitutions when compared with the rodent sequence. OX2 receptor is indeed a high-affinity receptor for human orexin B, with an IC
50
of 36 nM in the binding assay and an EC
50
of 60 nM in the [Ca
2+
]i transient assay. Human Orexin B has significantly lower affinity for the human OX1: the calculated IC
50
in the competitive binding assay and the EC
50
in the [Ca
2+
]i transient assay are 420 nM and 2500 nM for human orexin-B, respectively.
Human Orexin B significantly augments food intake; at the 2 hr time point, 5- and 12-fold stimulation of food consumption is observed by 3 nM and 30 nM orexin-B, respectively.
参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
食欲肽B (人)
上下游产品信息
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食欲肽B (人)
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食欲肽B (人)国内生产厂家
205640-91-1, 食欲肽B (人) 相关搜索:
促食素A 乙酰丙酮银 异腈基乙酸甲酯 异氰基乙酸乙酯 三乙酰丙酮铝 异氰酸叔丁酯 苄异腈 三乙酰丙酮铁 乙酰丙酮铬盐 异腈基正丁烷 三(2,2,6,6-四甲基-3,5-庚二酸)铕 1,1,3,3-四甲基丁基异氰 双水杨酰胺乙基钴 乙二胺氯化铂 对甲基苯磺酰甲基异腈 2,2,6,6-四甲基-3,5-庚烷二酸镝 苯硒酚 乙酰丙酮钴水合物
- Orexin receptor
- Peptide
- proteins
- 目录肽
- 标准品
- 其他生化试剂
- 多肽
- 生化试剂
- C123H212N44O35S1
- C123H212N44O35S
- 食欲素B(人类)三氟乙酸盐
- RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 (TRIFLUOROACETATE SALT)
- 人OREXIN B
- 食欲肽B(人) ≥98%, ≥98% (HPLC)
- 食欲肽B (人)
- 食欲肽B(人) ≥98%
- 205640-91-1
- OREXIN B (HUMAN) USP/EP/BP
- L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
- Human orexin B
- Orexin B (human) (trifluoroacetate salt)
- PubChem ID: 90479794
- Orexin B (human), ≥98% (HPLC)
- OREXIN B (HUMAN)
- OREXINS OREXIN B HUMAN
- RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
- H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
- HYPOCRETIN-2, HUMAN
- HYPOCRETIN-2
- ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
- OREXIN B HUMAN ≥98%
- Orexin B (huMan)
Hypocretin-2 (huMan)
- REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2