波生坦羟甲基杂质
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- CAS号:
- 253688-60-7
- 英文名:
- Hydroxy Bosentan
- 英文别名:
- Ro 48-863;Ro 48-8634;Bosentan Hydroxy;13C2,2H4]-Hydroxybosentan;Bosentan-Hydroxy methyl-Imp;Bosentan HydroxyMethyl IMpurity;Bosentan Impurity 2(Hydroxy Bosentan);4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide;Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-;N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
- 中文名:
- 波生坦羟甲基杂质
- 中文别名:
- 波生坦羟基;伯森坦杂质;羟基波生坦;波生坦杂质9;玻色羟甲基杂质;波生坦羟甲基杂质;波生坦羟基甲基杂质;波生坦杂质2(波生坦羟甲基);13C2,2H4]-羟基波生坦
- CBNumber:
- CB31176361
- 分子式:
- C27H29N5O7S
- 分子量:
- 567.61
- MOL File:
- 253688-60-7.mol
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波生坦羟甲基杂质化学性质
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熔点:
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128-132°C
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沸点:
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783.9±70.0 °C(Predicted)
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密度:
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1.372±0.06 g/cm3(Predicted)
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储存条件:
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-20°C Freezer, Under Inert Atmosphere
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溶解度:
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DMSO: soluble
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形态:
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A crystalline solid
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酸度系数(pKa):
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3.90±0.10(Predicted)
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波生坦羟甲基杂质性质、用途与生产工艺
Hydroxy bosentan (Ro 48-5033) 是 Bosentan (BOS) 被肝脏中的细胞色素 P450 系统代谢的后的主要代谢产物。Ro 48-5033 在药理上协助 BOS，保留 10％-20％ 的活性。
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Human Endogenous Metabolite
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波生坦羟甲基杂质
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253688-60-7, 波生坦羟甲基杂质 相关搜索:
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Nucleotides
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Bases & Related Reagents
- Heterocycles
- Aromatics
- 标准品
- 抑制剂
- C27H29N5O7S
- 波生坦杂质2(波生坦羟甲基)
- 13C2,2H4]-羟基波生坦
- 波生坦杂质9
- 玻色羟甲基杂质
- 波生坦羟基
- 伯森坦杂质
- 波生坦羟基甲基杂质
- 波生坦羟甲基杂质
- 羟基波生坦
- 253688-60-7
- Bosentan Impurity 2(Hydroxy Bosentan)
- 13C2,2H4]-Hydroxybosentan
- Benzenesulfonamide, 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-
- N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
- Bosentan-Hydroxy methyl-Imp
- Bosentan Hydroxy
- Bosentan HydroxyMethyl IMpurity
- Ro 48-8634
- Ro 48-863
- 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide