N-单甲基-L-精氨酸单乙酸酯
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- CAS号:
- 53308-83-1
- 英文名:
- NG-MONOMETHYL-L-ARGININE ACETATE
- 英文别名:
- 904;NMMA;CP47;CP 47;CP-47;L-NMMA;ANO 1020;L-NMMA ACETATE;NG-ME-L-ARG, ACOH;NMMA ACETATE SALT
- 中文名:
- N-单甲基-L-精氨酸单乙酸酯
- 中文别名:
- 精氨酸杂质25(醋酸盐);NG-甲基-L-精氨酸醋酸盐;NG-单甲基-L-精氨酸乙酸酯;NG-单甲基-L-精氨酸醋酸盐;NG-单甲基-L-精氨酸乙酸盐;N-单甲基-L-精氨酸单乙酸酯;NG—单甲基—L—精氨酸醋酸盐 100MG;N5-[亚氨基(甲基氨基)甲基]-L-鸟氨酸单乙酸盐;NG-单甲基-L-精氨酸乙酸盐;N蠅-MONOMETHYL-L-ARGININE ACETATE
- CBNumber:
- CB3138560
- 分子式:
- C9H20N4O4
- 分子量:
- 248.28
- MOL File:
- 53308-83-1.mol
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N-单甲基-L-精氨酸单乙酸酯化学性质
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熔点:
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180-190 °C
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比旋光度:
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D22 +9.5° (c = 0.10 in water)
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沸点:
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391.35°C (rough estimate)
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密度:
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1.2162 (rough estimate)
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折射率:
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1.6300 (estimate)
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储存条件:
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2-8°C
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溶解度:
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H2O: 1 mg/mL, clear, colorless
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形态:
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Powder
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颜色:
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White to Off-white
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水溶解性:
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Soluble in water (50 mM)
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BRN:
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6674255
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稳定性:
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Store at - 5°C; Desiccate Recommended
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InChIKey:
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IKPNWIGTWUZCKM-JEDNCBNOSA-N
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N-单甲基-L-精氨酸单乙酸酯性质、用途与生产工艺
L-NMMA acetate是一氧化氮合酶 (nitric oxide synthase) 抑制剂, 抑制一氧化氮合酶的所有亚型NOS1，NOS2和NOS3。对nNOS (大鼠), eNOS (人), and iNOS (小鼠) 的Ki 值分别为0.18，0.4，6 µM。
Ki: 0.18 µM (nNOS), 0.4 µM (eNOS), 6 µM (iNOS)
L-NMMA, starting from 100 μM, produces a concentration-dependent inhibition of the evoked relaxations (2Hz); maximal inhibition at 1 mM averaged about 35%. The inhibitory effect of L-NMMA is unchanged by previous incubation with D-arginine while it is prevented by L-arginine (L-Arg). L-NMMA does not affect isoprenaline-induced relaxation. Superfusion of L-NMMA reduces arteriolar diameter and causes dose-dependent increases in arteriolar tone. The onset of action of L-NMMA is nearly immediate. L-NMMA inhibits vasodilator responses to the endothelium-dependent vasodilator ACh but not to the endothelium-independent NP. NE induced dose-related vasoconstriction that is significantly potentiated by L-NMMA.
N-单甲基-L-精氨酸单乙酸酯
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-18732A | L-NMMA acetate | | 1 mg | 361元 |
| 2024/01/25 | HY-18732A | N-单甲基-L-精氨酸单乙酸酯
L-NMMA acetate | 53308-83-1 | 5mg | 950元 |
53308-83-1, N-单甲基-L-精氨酸单乙酸酯 相关搜索:
- Signalling
- Nitric Oxide Reagents
- Amino Acids & Derivatives
- Amino Acids 13C, 2H, 15N
- 生化试剂
- 合成
- Biochemicals and Reagents
- Nitric Oxide Synthase (iNOS)
- I - Z
- Modified Amino Acids
- L to O
- Enzyme Inhibitors
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors by Enzyme
- Amino Acids and Peptides
- BioChemical
- Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine.
- C7H16N4O2C2H4O2
- C9H20N4O4
- C7H18N4O2
- NG-单甲基-L-精氨酸乙酸酯
- 精氨酸杂质25(醋酸盐)
- NG—单甲基—L—精氨酸醋酸盐 100MG
- N5-[亚氨基(甲基氨基)甲基]-L-鸟氨酸单乙酸盐
- NG-甲基-L-精氨酸醋酸盐
- NG-单甲基-L-精氨酸醋酸盐
- NG-单甲基-L-精氨酸乙酸盐
- N蠅-MONOMETHYL-L-ARGININE ACETATE
- NG-单甲基-L-精氨酸乙酸盐
- N-单甲基-L-精氨酸单乙酸酯
- 53308-83-1
- Arginine impurity 25 (acetate)
- CP-47
- CP47
- CP 47
- 904
- (2S)-5-{[(E)-amino(methyliminio)methyl]amino}-2-ammoniopentanoate
- NG-MONOMETHYL-L-ARGININE ACETATE USP/EP/BP
- N-omega-Monomethyl-L-arginine monoacetate, 99%
- Nω-Methyl-L-arginine Acetate
- Methylarginine acetate
- Nω-Monomethyl-L-arginineAcetate>
- H-L-Arg(Me)-OH acetate
- NG-Monomethyl-L-arginine, Monoacetate Salt - CAS 53308-83-1 - Calbiochem
- Tilarginine Acetate
- N5-[Imino(methylamino)methyl]-L-ornithine Acetate
- ANO 1020
- H-ARG(ME)-OH ACOH
- L-NMMA, ACETATE SALT
- L-NMMA ACETATE
- L-NMMA
- L-NMMA, MONOACETATE SALT
- L-NMMA MONOACETATE
- L-NG-MONOMETHYLARGININE, ACETATE SALT
- NW-METHYL-L-ARGININE
- N-Monomethyl-L-arginine monoacetate.
- nω-methyl-l-arginine acetate salt
- N-OMEGA-METHYL-L-ARGININE ACETATE