GALANIN (1-13) - BRADYKININ (2-9) AMIDE
|
|
|
- CAS号:
- 142846-71-7
- 英文名:
- M35
- 英文别名:
- M35;GWTLNSAGYLLGPPPGFSPFR-NH2;Galanin receptorligand M35;GALANIN (1-13)-BRADYKININ (2-9) AMIDE;Galanin (1-13)-Bradykinin (2-9), amide, M35;GALANIN FRAGMENT (1-13)-BRADYKININ*FRAGMENT (2-9)AM;GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2;L-Argininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-
- 中文名:
- GALANIN (1-13) - BRADYKININ (2-9) AMIDE
- 中文别名:
- M35肽;甘丙肽(1-13)-缓激肽(2-9)酰胺
- CBNumber:
- CB3215663
- 分子式:
- C107H153N27O26
- 分子量:
- 2233.52
- MOL File:
- 142846-71-7.mol
|
|
|
GALANIN (1-13) - BRADYKININ (2-9) AMIDE化学性质
-
储存条件:
-
−20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
形态:
-
solid
-
|
GALANIN (1-13) - BRADYKININ (2-9) AMIDE性质、用途与生产工艺
Galanin Receptor Ligand M35 是一种高亲和力的甘丙肽受体 (galanin receptor) 配体 (Kd=0.1 nM)，也是 galanin receptor 拮抗剂。Galanin Receptor Ligand M35 对人甘丙肽受体 1 型 和 人甘丙肽受体 2 型 的 Ki 值分别为 0.11 nM、2.0 nM。
Kd: 0.1 nM (galanin receptor)
Ki: 0.11 nM (human galanin receptor type 1), 2.0 nM (human galanin receptor type 2)
Galanin Receptor Ligand M35 has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10 nM), Galanin Receptor Ligand M35 at low concentrations (1 nM) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30 nM), Galanin Receptor Ligand M35 acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP.
Galanin Receptor Ligand M35 (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task.
GALANIN (1-13) - BRADYKININ (2-9) AMIDE
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE
Galanin Receptor Ligand M35 | 142846-71-7 | 1mg | 2000元 |
| 2024/01/25 | HY-P1840 | GALANIN (1-13) - BRADYKININ (2-9) AMIDE
Galanin Receptor Ligand M35 | 142846-71-7 | 5mg | 4200元 |
GALANIN (1-13) - BRADYKININ (2-9) AMIDE
生产厂家
142846-71-7, GALANIN (1-13) - BRADYKININ (2-9) AMIDE 相关搜索:
- Neuropeptides
- Galanins
- Peptide
- Galanin receptor
- Peptides for Cell Biology
- 目录肽
- 多肽
- Galanins
- Gastrointestinal Products
- Peptides
- Biochemicals and Reagents
- Amino Acids and Peptides
- BioChemical
- C107H153N27O26
- 甘丙肽(1-13)-缓激肽(2-9)酰胺
- M35肽
- 142846-71-7
- L-Argininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-
- Galanin (1-13)-Bradykinin (2-9), amide, M35
- Galanin receptorligand M35
- GALANIN FRAGMENT (1-13)-BRADYKININ*FRAGMENT (2-9)AM
- GWTLNSAGYLLGPPPGFSPFR-NH2
- GALANIN (1-13)-BRADYKININ (2-9) AMIDE
- GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2
- H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2
- M35