ANTI-ALPHA-ACTININ 抗体

ANTI-ALPHA-ACTININ 抗体性质、用途与生产工艺

描述

小鼠单克隆抗体 to alpha Actinin

宿主

Mouse

验证的应用

Mouse

种属反应性

与反应: Mouse, Rat, Human, African green monkey

免疫原

Recombinant fragment corresponding to Human alpha Actinin/ACTN1 aa 650-893. Protein produced in E.coli. Database link: NP_001093

品牌示例

Western blot - Anti-alpha Actinin/ACTN1 antibody(ab90421)

All lanes : Anti-alpha Actinin/ACTN1 antibody [OTI7A4] (ab90421) at 1/200 dilution
Lane 1 : HepG2 (Human liver hepatocellular carcinoma cell line) extracts
Lane 2 : HeLa (Human epithelial cell line from cervix adenocarcinoma) extracts
Lane 3 : SVT2 (Mouse cell line) extracts
Lane 4 : A549 (Human lung carcinoma cell line) extracts
Lane 5 : COS-7 (African green monkey kidney fibroblast-like cell line) extracts
Lane 6 : Jurkat (Human T cell leukemia cell line from peripheral blood) extracts
Lane 7 : PC-12 (Rat adrenal gland pheochromocytoma cell line) extracts
Lane 8 : MCF7 (Human breast adenocarcinoma cell line) extracts
Lysates/proteins at 10 µg per lane.
Predicted band size: 103 kDa

背景

辅肌动蛋白有辅肌动蛋白-1、2、3和4四种类型,呈细胞或组织特异性分布.这四种蛋白的共同结构特征是在细胞内均为反向平行的二聚体,并具有N末端肌动蛋白结合结构域(ABD)、血影蛋白样中央重复结构域和C末端"EF手"结构域。
作为细胞骨架中一种重要的肌动蛋白交联蛋白,辅肌动蛋白通过与其相关蛋白包括整合素(integrins)、钙粘素(cadherin)以及细胞信号传导通路中的信号分子等,例如斑联蛋白（zyxin）的协同作用,在稳定细胞粘附、调节细胞形状及细胞运动中发挥着重要作用。因此,肿瘤的发生、发展和恶化与辅肌动蛋白的结构、功能密切相关。

应用

ANTI-ALPHA-ACTININ用于2型糖尿病患者尿液α-actinin-4含量与糖尿病痛病相关性探讨研究。

ANTI-ALPHA-ACTININ 抗体 上下游产品信息

上游原料

下游产品

ANTI-ALPHA-ACTININ 抗体 生产厂家

 

ANTI-ALPHA-ACTININ 抗体 相关搜索:

• Clone Index
• Antibodies to Actin-associated Proteins/MyosinAntibodies
• BCardiac Stem Cell Biology
• Cardiogenesis Markers
• Cardiac Stem Cell Tracking
• Antibodies to Cytoskeleton
• Antibodies
• Alphabetical Index
• A1-ALCell Biology
• Antibodies to Actin-associated Proteins/MyosinCardiac Stem Cell Biology
• Monoclonal Anti-α-Actinin antibody produced in mouse
• Anti-α-Actinin antibody produced in rabbit
• ANTI-HUMAN ACTIN, ALPHA SMOOTH MUSCLE
• ANTI-HUMAN ALPHA-ACTININ
• ANTI-HUMAN ALPHA SMOOTH MUSCLE ACTIN
• ANTI-HUMAN ALPHA SMOOTH MUSCLE
• ANTI-BOVINE ALPHA-ACTININ
• ANTI-ALPHA-ACTIN MOUSE MAB
• ANTI-ALPHA-ACTININ MOUSE MAB
• ANTI-ALPHA-ACTININ, CHICKEN GIZZARD
• ANTI-ALPHA-ACTININ, CHICKEN
• ANTI-ALPHA-ACTININ
• ANTI-ALPHA-ACTIN, HUMAN SMOOTH MUSCLE (MOUSE)
• ANTI-ALPHA-ACTIN, HUMAN SMOOTH MUSCLE
• ANTI-ASMA SMOOTH MUSCLE, HUMAN
• ANTI-CHICKEN ALPHA-ACTININ
• ALPHA-ACTININ (AB-1) MONOCLONAL ANTIBODY
• ANTI-ACTININ, ALPHA
• ANTI-ACTIN-ALPHA (SMOOTH MUSCLE, HUMAN)
• ANTI-ACTIN, ALPHA-, HUMAN, SMOOTH MUSCLE
• ANTI-ACTIN, SMOOTH MUSCLE (AB-2)
• ANTI-ACTIN (SMOOTH MUSCLE)
• MONOCLONAL ANTI-ACTIN, ALPHA-SMOOTH MUSCLE
• MS X ANTI-ACTIN