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羟基脒双(甲磺酸)

羟基脒双(甲磺酸), 223769-64-0, 结构式
羟基脒双(甲磺酸)
CAS号:
223769-64-0
英文名:
HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
英文别名:
Fluoro-Gold;Hydroxystilbamidine *CAS 223769-64-0*;4-[(E)-2-(4-Carbamimidoylphenyl)ethenyl]-3-hydroxybenzene-1-carboximidamide;HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe];4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate);HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
中文名:
羟基脒双(甲磺酸)
中文别名:
荧光金;羟基脒双(甲磺酸);羟芪巴脒*DNA和RNA染料*;4-(2-(4-(氨基亚氨基)苯基)乙烯基)-3-羟基苯甲脒二甲磺酸盐
CBNumber:
CB32719747
分子式:
C17H20N4O4S
分子量:
376.43
MOL File:
223769-64-0.mol

羟基脒双(甲磺酸)化学性质

储存条件:
2-8°C
溶解度:
Water: soluble
形态:
A powder
安全信息
危险品标志: Xi
危险类别码: 36/37/38
安全说明: 26-36
WGK Germany: 3

羟基脒双(甲磺酸)性质、用途与生产工艺

生物活性

Hydroxystilbamidine bis(methanesulfonate) 是一种能够结合 DNA 和 RNA 的染料, 也被发现是细胞核糖核酸酶的强效抑制剂。

体外研究

It is found that the trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) permits the recovery of mRNA after polysome released with Nonidet P-40 (NP-40). Sucrose gradient analysis of detergent-lysed postnuclear supernates is used to analyze the size distribution of NP-40-released polysomes. The heparin gradient shows some polyribosomes, whereas the Hydroxystilbamidine bis(methanesulfonate) gradient shows a remarkably large peak of very heavy polyribosomes. This peak is obtained reproducibly if Hydroxystilbamidine bis(methanesulfonate) is present before the addition of NP-40.

体内研究

Hydroxystilbamidine bis(methanesulfonate) is an effective suppressor of the plaque-forming cell (PFC) response when given before sheep erythrocytes (SRBC) stimulation. Hydroxystilbamidine bis(methanesulfonate) depresses the plaque response of the treated mice. Fewer PFC are observed in Hydroxystilbamidine bis(methanesulfonate)-treated mice throughout the experiment, but the level of suppression decreases with time. By day 14, the number of PFC observed in both the Hydroxystilbamidine bis(methanesulfonate) treated mice and the control group is essentially at the background level.

羟基脒双(甲磺酸) 上下游产品信息

上游原料

下游产品


羟基脒双(甲磺酸) 生产厂家

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223769-64-0, 羟基脒双(甲磺酸) 相关搜索:

  • 分子生化产品
  • 荧光探针,标记,颗粒和染色
  • 荧光金
  • 4-(2-(4-(氨基亚氨基)苯基)乙烯基)-3-羟基苯甲脒二甲磺酸盐
  • 羟基脒双(甲磺酸)
  • 羟芪巴脒*DNA和RNA染料*
  • 223769-64-0
  • 4-[(E)-2-(4-Carbamimidoylphenyl)ethenyl]-3-hydroxybenzene-1-carboximidamide
  • HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
  • Hydroxystilbamidine *CAS 223769-64-0*
  • 4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
  • Fluoro-Gold
  • HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
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