158364-59-1
|
|
|
- CAS号:
- 158364-59-1
- 英文名:
- Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester
- 英文别名:
- PUMAPRAZOLE;inhibit,Proton Pump,BY 841,Pumaprazole,BY841,Inhibitor;Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester
- 中文名:
- 158364-59-1
- 中文别名:
- 普马拉唑;化合物 T16682
- CBNumber:
- CB33285508
- 分子式:
- C19H22N4O2
- 分子量:
- 338.4
- MOL File:
- 158364-59-1.mol
|
|
|
158364-59-1化学性质
-
密度:
-
1.21±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
酸度系数(pKa):
-
13.67±0.70(Predicted)
-
|
158364-59-1性质、用途与生产工艺
Pumaprazole 是一种可逆性质子泵拮抗剂。
Pumaprazole is a reversible proton pump antagonist. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compare to ranitidine. Pumaprazole displays identical ID
50
values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23) and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect.
158364-59-1
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-19223 | 普马拉唑
Pumaprazole | 158364-59-1 | 1mg | 3000元 |
| 2024/04/30 | HY-19223 | 普马拉唑
Pumaprazole | 158364-59-1 | 5mg | 6900元 |
158364-59-1, 158364-59-1 相关搜索:
- 化合物 T16682
- 普马拉唑
- 158364-59-1
- inhibit,Proton Pump,BY 841,Pumaprazole,BY841,Inhibitor
- PUMAPRAZOLE
- Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester