(R)-(-)-2-氨基-5-膦酰戊酸
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- CAS号:
- 79055-68-8
- 英文名:
- D-AP5
- 英文别名:
- EIF4G2;D-AP5;IF4G2;D-APV;(R)-AP-5;Emasol L10;Emasol L 10;Emasol L-10;5-Phosphono-D-norvaline;D-Norvaline, 5-phosphono-
- 中文名:
- (R)-(-)-2-氨基-5-膦酰戊酸
- 中文别名:
- 5-膦酰基-D-正缬氨酸;D(-)-2-氨基-5-膦戊酸;(R)-2-氨基-5-膦酸戊酸;D-AP5,NMDA谷氨酸位点拮抗剂;(R)-(-)-2-氨基-5-膦酰戊酸;ANTI-DAP5 ANTIBODY-死亡相关蛋白5抗体
- CBNumber:
- CB3371309
- 分子式:
- C5H12NO5P
- 分子量:
- 197.13
- MOL File:
- 79055-68-8.mol
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(R)-(-)-2-氨基-5-膦酰戊酸化学性质
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熔点:
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approximate 233℃
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沸点:
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482.1±55.0 °C(Predicted)
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密度:
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1.529±0.06 g/cm3(Predicted)
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RTECS号:
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RD2513000
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储存条件:
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Store at RT
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溶解度:
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Soluble to 100 mM in sterile
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形态:
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White solid
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酸度系数(pKa):
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2.46±0.10(Predicted)
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颜色:
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White
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水溶解性:
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Soluble in water (100mM)
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敏感性:
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Light Sensitive
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(R)-(-)-2-氨基-5-膦酰戊酸性质、用途与生产工艺
D-AP5 (D-APV) 是一种选择性和竞争性 NMDA 受体拮抗剂，Kd 为 1.4 μM。D-AP5 抑制 NMDA 受体的谷氨酸结合位点。
D-AP5 is a NMDA receptor antagonist. Chronic intraventricular infusion of D-AP5 causes a parallel dose-dependent impairment of spatial learning and long-term potentiation (LTP)
in vivo
. Intracerebral concentrations of D-AP5 fail to induce any measurable sensorimotor disturbance when spatial learning is prevented.
D-AP5 infusion is associated with a progressive reduction in swim speed over trials. D-AP5 causes sensorimotor disturbances in the spatial task, but these gradually worsened as the animals fail to learn. Rats treated with D-AP5 show a delay-dependent deficit in spatial memory in the delayed matching-to-place protocol for the water maze.
(R)-(-)-2-氨基-5-膦酰戊酸
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-100714A | D-AP5 | | 1 mg | 304元 |
| 2024/01/25 | HY-100714A | (R)-(-)-2-氨基-5-膦酰戊酸
D-AP5 | 79055-68-8 | 5mg | 950元 |
79055-68-8, (R)-(-)-2-氨基-5-膦酰戊酸 相关搜索:
- Glutamate receptor
- Glutamate
- 生化试剂
- 抗体-一抗
- 小分子
- 试剂盒-细胞分析试剂盒
- 化工原料
- 合成
- C5H12NO5P
- D-AP5,NMDA谷氨酸位点拮抗剂
- D(-)-2-氨基-5-膦戊酸
- ANTI-DAP5 ANTIBODY-死亡相关蛋白5抗体
- (R)-2-氨基-5-膦酸戊酸
- 5-膦酰基-D-正缬氨酸
- (R)-(-)-2-氨基-5-膦酰戊酸
- 79055-68-8
- EIF4G2
- Emasol L-10
- Emasol L10
- Emasol L 10
- D-Norvaline, 5-phosphono-
- D(-)-2-AMINO-5-PHOSPHONOVALERIC ACID (D-AP5);5-PHOSPHONO-D-NORVALINE
- 5-Phosphono-D-norvaline
- D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem
- D(-)-2-AMINO-5-PHOSPHONOPENTANOIC AC
- D(-)-2-Amino-5-phosphonovaleric acid hydrate,96%, (>98% ee)
- D-APV
- (R)-AP-5
- (R)-5-Phosphono-2-aminovaleric acid
- (R)-2-Amino-5-phosphonovaleric acid
- (2R)-2-Amino-5-phosphonovaleric acid
- D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)
- IF4G2
- Eukaryotic translation initiation factor 4 γ 2
- Death associated protein 5
- Anti-EIF4G2, N-Terminal antibody produced in rabbit
- (2R)-2-aMMonio-5-phosphonatopentanoate
- (R)-2-aMino-5-phosphonopentanoic acid
- D(-)-AP-5, D(-)-APV, D-2-Amino-5-phosphonovaleric acid
- D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID (D-AP5)
- D(-)-2-Amino-5-phosphonovaleric acid hydrate
- D-(-)-2-AMINO-5-PHOSPHONOVALERIC ACID
- D-2-AMINO-5-PHOSPHONOPENTANOIC ACID
- D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID
- D-AP5