5-硝基-2-(3-苯丙胺)苯甲酸
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- CAS号:
- 107254-86-4
- 英文名:
- NPPB
- 英文别名:
- NPPB;C13705;Compound 144;Recombinant Human NPPB Protein, His Tag;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID;5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID;3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid;5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%
- 中文名:
- 5-硝基-2-(3-苯丙胺)苯甲酸
- 中文别名:
- 5-硝基-2-(3-苯丙胺)苯甲酸;5-硝基-2-((3-苯基丙基)氨基)苯甲酸
- CBNumber:
- CB3450426
- 分子式:
- C16H16N2O4
- 分子量:
- 300.31
- MOL File:
- 107254-86-4.mol
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5-硝基-2-(3-苯丙胺)苯甲酸化学性质
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熔点:
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178-180℃
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沸点:
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523.5±50.0 °C(Predicted)
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密度:
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1.323±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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ethanol: 3 mg/mL
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酸度系数(pKa):
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2.27±0.22(Predicted)
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形态:
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Yellow solid
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5-硝基-2-(3-苯丙胺)苯甲酸性质、用途与生产工艺
NPPB 是外向整流氯化物通道 (ORCC) 的阻断剂。
0.1 mM NPPB in the bath solution reduces channel open probability from 0.89±0.06 to 0.11±0.04 (n=5, P<0.01). Dose-dependent inhibition of chloride currents is observed with a 50% inhibitory concentration (IC
50
) of 125 μM NPPB. NPPB itself also shows cytotoxicity against glioma cells with a GI
50
of approximately 500 μM.
5-硝基-2-(3-苯丙胺)苯甲酸
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-101012 | NPPB | | 5 mg | 343元 |
| 2024/01/25 | HY-101012 | 5-硝基-2-(3-苯丙胺)苯甲酸
NPPB | 107254-86-4 | 10mg | 550元 |
107254-86-4, 5-硝基-2-(3-苯丙胺)苯甲酸 相关搜索:
- Chloride channel
- 合成有机化合物配体
- Voltage-gated Ion Channels
- Ion Channels
- Monovalent Ion Channels
- Chloride Channel Modulators
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- 5-硝基-2-((3-苯基丙基)氨基)苯甲酸
- 5-硝基-2-(3-苯丙胺)苯甲酸
- 107254-86-4
- Recombinant Human NT-proBNP/NPPB Protein, His & Flag Tag
- Recombinant Human NPPB Protein, His Tag
- Benzoic acid, 5-nitro-2-[(3-phenylpropyl)amino]-
- 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem
- 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE
- 5-Nitro-2-(3-phenylpropylaMino)benzoic acid, 5-nitro-2-[(3-phenylpropyl)aMino]benzoic acid, Benzoic acid
- 5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB
- C13705
- Compound 144
- 3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid
- 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%
- 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN
- NPPB
- 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID
- 5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID