1609563-71-4
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- CAS号:
- 1609563-71-4
- 英文名:
- (1R,2R)-2-PCCA(hydrochloride)
- 英文别名:
- (1R,2R)-2-PCCA 2HCl;2R)-2-PCCA(hydrochloride);(1R,2R)-2-PCCA(hydrochloride);(1R,2R)2PCCA hydrochloride,(1R,2R) 2 PCCA hydrochloride
- 中文名:
- 1609563-71-4
- 中文别名:
- 化合物 T13423;(1R,2R)-2-PCCA盐酸盐;(1R,2R)-N-((2S,3S)-2-氨基-3-甲基戊基)-N-(4'-丙基-[1,1'-联苯]-4-基)-2(吡啶-2-基)环丙酰胺二盐酸盐
- CBNumber:
- CB34796629
- 分子式:
- C30H38ClN3O
- 分子量:
- 492.1
- MOL File:
- 1609563-71-4.mol
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1609563-71-4化学性质
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储存条件:
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under inert gas (nitrogen or Argon) at 2-8°C
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溶解度:
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DMSO : 50 mg/mL (94.60 mM)
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1609563-71-4性质、用途与生产工艺
(1R,2R)-2-PCCA hydrochloride 是一种有效的 GPR88 受体激动剂，非细胞体系下，EC50 值为 3 nM，细胞体系下 EC50 值为 603 nM。
EC50: 3 nM (GPR88 receptor), 603 nM (GPR88 receptor, in GPR88-22F cells)
(1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an EC
50
of 3 nM in cell-free assay, and 603 nM in cell assay. (1R,2R)-2-PCCA inhibits GPR88-mediated cAMP production through a Gαi-coupled pathway, with an EC
50
of 56 nM in HEK293 cells stably expressing the human GPR88 receptor and the GloSensor-22F cAMP construct.
1609563-71-4
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-100013A1 | (1R,2R)-2-PCCA hydrochloride | | 1 mg | 900元 |
| 2024/04/30 | HY-100013A1 | 1609563-71-4
(1R,2R)-2-PCCA hydrochloride | 1609563-71-4 | 10mM * 1mLin DMSO | 2090元 |
1609563-71-4, 1609563-71-4 相关搜索:
- (1R,2R)-2-PCCA盐酸盐
- 化合物 T13423
- (1R,2R)-N-((2S,3S)-2-氨基-3-甲基戊基)-N-(4'-丙基-[1,1'-联苯]-4-基)-2(吡啶-2-基)环丙酰胺二盐酸盐
- 1609563-71-4
- (1R,2R)2PCCA hydrochloride,(1R,2R) 2 PCCA hydrochloride
- 2R)-2-PCCA(hydrochloride)
- (1R,2R)-2-PCCA 2HCl
- (1R,2R)-2-PCCA(hydrochloride)