FASN inhibitor 1
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- CAS号:
- 2097262-60-5
- 英文名:
- FASN inhibitor 1
- 英文别名:
- FASN-IN-3;FASN inhibitor 1;Fatty Acid Synthase (FASN),Inhibitor,inhibit,FASNIN3,FASN IN 3;4-(1-(5-(3,4-Dimethyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoyl)azetidin-3-yl)benzonitrile;Benzonitrile, 4-[1-[5-(3,4-dimethyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoyl]-3-azetidinyl]-
- 中文名:
- FASN inhibitor 1
- 中文别名:
- 化合物FASN-IN-3;4-(1-(5-(3,4-二甲基-1H-吡唑-5-基0-2,4-二甲基苯甲酰基)氮杂环丁烷-3-基)苯甲腈
- CBNumber:
- CB34797055
- 分子式:
- C24H24N4O
- 分子量:
- 384.47
- MOL File:
- 2097262-60-5.mol
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FASN inhibitor 1化学性质
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沸点:
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641.5±55.0 °C(Predicted)
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密度:
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1.26±0.1 g/cm3(Predicted)
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酸度系数(pKa):
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14.66±0.50(Predicted)
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FASN inhibitor 1性质、用途与生产工艺
FASN-IN-3 是一种脂肪酸合酶 (FASN) 抑制剂，详细信息请参考专利文献 US20170119786A1 中的化合物 242A。
Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 (Compound 242A), results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation. For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.
FASN inhibitor 1
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/25 | HY-U00436 | FASN-IN-3 | | 1 mg | 1400元 |
| 2024/01/25 | HY-U00436 | FASN inhibitor 1
FASN-IN-3 | 2097262-60-5 | 5mg | 3500元 |
2097262-60-5, FASN inhibitor 1 相关搜索:
- 4-(1-(5-(3,4-二甲基-1H-吡唑-5-基0-2,4-二甲基苯甲酰基)氮杂环丁烷-3-基)苯甲腈
- 化合物FASN-IN-3
- 2097262-60-5
- Fatty Acid Synthase (FASN),Inhibitor,inhibit,FASNIN3,FASN IN 3
- 4-(1-(5-(3,4-Dimethyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoyl)azetidin-3-yl)benzonitrile
- Benzonitrile, 4-[1-[5-(3,4-dimethyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoyl]-3-azetidinyl]-
- FASN-IN-3
- FASN inhibitor 1