HMR 1556
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- CAS号:
- 223749-46-0
- 英文名:
- N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide
- 英文别名:
- HMR 1556;HMR-1556 >=98% (HPLC);N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide;Methanesulfonamide, N-[(3R,4S)-3,4-dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methyl-
- 中文名:
- HMR 1556
- 中文别名:
- 化合物 T15487
- CBNumber:
- CB34902859
- 分子式:
- C17H24F3NO5S
- 分子量:
- 411.44
- MOL File:
- 223749-46-0.mol
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HMR 1556化学性质
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熔点:
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178-179 °C
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沸点:
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469.0±55.0 °C(Predicted)
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密度:
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1.35±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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13.30±0.60(Predicted)
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HMR 1556性质、用途与生产工艺
HMR 1556 是色氨醇衍生物，是一种有效的 IKs 阻滞剂，在犬和豚鼠的左心室肌细胞中的 IC50 值分别为 10.5 nM、34 nM。
IC50: 10.5 nM (I
Ks
in canine left ventricular myocytes), 34 nM (I
Ks
in guinea pig left ventricular myocytes)
HMR 1556 inhibits I
to
, I
Ca,L
and IKr with IC
50
s of 33.9 μM, 27.5 μM, 12.6 μM in canine left ventricular myocytes, respectively.
HMR 1556
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-106369 | HMR 1556 | | 1 mg | 681元 |
| 2024/01/25 | HY-106369 | HMR 1556
HMR 1556 | 223749-46-0 | 5mg | 1500元 |
223749-46-0, HMR 1556 相关搜索:
- C17H24F3NO5S
- 化合物 T15487
- 223749-46-0
- HMR-1556 >=98% (HPLC)
- Methanesulfonamide, N-[(3R,4S)-3,4-dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methyl-
- N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide
- HMR 1556