3-氯-4-氟苯基溴化镁
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- CAS号:
- 413589-34-1
- 英文名:
- 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID&
- 英文别名:
- broMo(3-chloro-4-fluorophenyl)MagnesiuM;3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID&;3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID&magnesium,1-chloro-2-fluorobenzene-5-ide,bromide;3-chloro-4-fluorophenylmagnesium bromide solution;3-Chloro-4-fluorophenylmagnesium bromide, 0.5 M in THF;3-Chloro-4-fluorophenylmagnesium bromide, 0.50 M in THF;3-Chloro-4-fluorophenylMagnesiuM broMide, 0.50 M in 2-MeTHF;3-Chloro-4-fluorophenylmagnesium bromide solution 0.5 in THF;3-Chloro-4-fluorophenylmagnesium bromide solution 0.5 M in THF
- 中文名:
- 3-氯-4-氟苯基溴化镁
- 中文别名:
- 3-氯-4-氟苯基溴化镁;3-氯-4-氟苯基溴化镁溶液;3-氯-4-氟苯基溴化镁 0.5M THF;3-氯-4-氟苯基溴化镁 0.5M 四氢呋喃;3-氯-4-氟苯基异丙溴化镁, 0.50 M 2-METHF 溶液;3-氯-4-氟苯基溴化镁, 0.5 M SOLUTION IN THF, SPCSEAL
- CBNumber:
- CB3504918
- 分子式:
- C6H3BrClFMg
- 分子量:
- 233.7484232
- MOL File:
- 413589-34-1.mol
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3-氯-4-氟苯基溴化镁化学性质
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沸点:
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65 °C
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密度:
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0.966 g/mL at 25 °C
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闪点:
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1 °F
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储存条件:
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2-8°C
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3-氯-4-氟苯基溴化镁性质、用途与生产工艺
3-氯-4-氟苯基溴化镁可用作医药合成中间体，如可用于制备吡咯烷衍生物如(2R，5S)-1-(叔丁氧羰基)-5-(3-氯-4-氟苯基)吡咯烷-2-羧酸乙酯，该化合物具有肽降钙素基因相关肽(CGRP)受体拮抗作用，可用作治疗与CGRP受体相关的各种疾病。
在氩气氛下，向镁(434mg)和THF(2mL)的混合物中加入微量碘。将此混合物加温至60℃后，滴加4-溴-2-氯-1-氟苯(3.58g)的THF(6.5mL)溶液(滴加期间温度保持在65℃)。将此混合物于60℃搅拌30分钟后，冷却至室温，得到3-氯-4-氟苯基溴化镁。
3-氯-4-氟苯基溴化镁
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/01/16 | H54700 | 3-氯-4-氟苯基异丙溴化镁, 0.50 M 2-MeTHF 溶液
3-Chloro-4-fluorophenylmagnesium bromide, 0.50 M in 2-MeTHF | 413589-34-1 | 100ml | 3834元 |
413589-34-1, 3-氯-4-氟苯基溴化镁 相关搜索:
- Organometallic Reagents
- Grignard Reagents
- Aryl
- Organometallic Reagents
- Grignard Reagents
- Chemical Synthesis
- Grignard Reagent
- 格式试剂
- 稳定同位素,超干溶剂
- 格氏试剂
- 3-氯-4-氟苯基溴化镁 0.5M 四氢呋喃
- 3-氯-4-氟苯基溴化镁, 0.5 M SOLUTION IN THF, SPCSEAL
- 3-氯-4-氟苯基异丙溴化镁, 0.50 M 2-METHF 溶液
- 3-氯-4-氟苯基溴化镁溶液
- 3-氯-4-氟苯基溴化镁
- 3-氯-4-氟苯基溴化镁 0.5M THF
- 413589-34-1
- 3-Chloro-4-fluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal&trade
- 3-Chloro-4-fluorophenylmagnesium bromide, 0.5 M in THF
- 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID&
- 3-Chloro-4-fluorophenylMagnesiuM broMide, 0.50 M in 2-MeTHF
- 3-Chloro-4-fluorophenylMagnesiuM broMide, 0.5 M solution in THF, SpcSeal
- broMo(3-chloro-4-fluorophenyl)MagnesiuM
- 3-Chloro-4-fluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal
- 3-Chloro-4-fluorophenylmagnesium bromide solution 0.5 in THF
- 3-chloro-4-fluorophenylmagnesium bromide solution
- 3-CHLORO-4-FLUOROPHENYLMAGNESIUM BROMID&
- magnesium,1-chloro-2-fluorobenzene-5-ide,bromide
- 3-Chloro-4-fluorophenylmagnesium bromide, 0.50 M in THF
- 3-Chloro-4-fluorophenylmagnesium bromide solution 0.5 M in THF