Methyl (4-bromobenzoyl)-L-cysteinate
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- CAS号:
- 1947408-74-3
- 英文名:
- Methyl (4-bromobenzoyl)-L-cysteinate
- 英文别名:
- Methyl (4-bromobenzoyl)-L-cysteinate;L-Cysteine, N-(4-bromobenzoyl)-, methyl ester;pharmacophore,inhibit,Cysteine thiol probe,products,enone-based,chromophore,thiol-based,electrophilic,Inhibitor,l-cystine,Natural
- 中文名:
- Methyl (4-bromobenzoyl)-L-cysteinate
- 中文别名:
- 化合物CYSTEINE THIOL PROBE;METHYL (4-BROMOBENZOYL)-L-CYSTEINATE
- CBNumber:
- CB35542274
- 分子式:
- C11H12BrNO3S
- 分子量:
- 318.19
- MOL File:
- 1947408-74-3.mol
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Methyl (4-bromobenzoyl)-L-cysteinate化学性质
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沸点:
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465.2±45.0 °C(Predicted)
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密度:
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1.491±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO: 250 mg/mL (785.69 mM)
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酸度系数(pKa):
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9.05±0.10(Predicted)
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Methyl (4-bromobenzoyl)-L-cysteinate性质、用途与生产工艺
Cysteine Thiol Probe 是一种基于硫醇的探针，旨在标记亲电子的天然产物。Cysteine Thiol Probe 具有理想药效团探针的每个特征，并具有发色团。Cysteine Thiol Probe 能够结合基于烯酮，β-内酰胺和 β-内酯的亲电子代谢物。
Cysteine Thiol Probe (Probe 1) reacts much more readily with β-lactam- and β-lactone-based electrophilic natural products, and its reactivity with epoxide-based electrophilic natural products is poor. And probe 2 reacts much faster with epoxide-containing natural products. This orthogonal reactivity allows them to be employed in extracts simultaneously. Since Cysteine Thiol Probe is brominated and probe 2 is chlorinated, the isotopic patterns of labeled natural products point toward their structural origin. Competition experiments using Cysteine Thiol Probe and 2 indicated that brominated Cysteine Thiol Probe reacted exclusively with the β-lactam in penicillin G and the β-lactone in salinosporamide A while chlorinated probe 2 alone reacted with the epoxide in salinamide A.
Methyl (4-bromobenzoyl)-L-cysteinate
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2023/01/06 | S0813 | Methyl (4-bromobenzoyl)-L-cysteinate
Cysteine thiol probe | 1947408-74-3 | 5mg | 4479.93元 |
| 2023/01/06 | S0813 | Methyl (4-bromobenzoyl)-L-cysteinate
Cysteine thiol probe | 1947408-74-3 | 25mg | 13505.3元 |
Methyl (4-bromobenzoyl)-L-cysteinate
生产厂家
1947408-74-3, Methyl (4-bromobenzoyl)-L-cysteinate 相关搜索:
- METHYL (4-BROMOBENZOYL)-L-CYSTEINATE
- 化合物CYSTEINE THIOL PROBE
- 1947408-74-3
- L-Cysteine, N-(4-bromobenzoyl)-, methyl ester
- pharmacophore,inhibit,Cysteine thiol probe,products,enone-based,chromophore,thiol-based,electrophilic,Inhibitor,l-cystine,Natural
- Methyl (4-bromobenzoyl)-L-cysteinate