H-ILE-PRO-PRO-OH
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- CAS号:
- 26001-32-1
- 英文名:
- H-ILE-PRO-PRO-OH
- 英文别名:
- Ile-Pro-Pro;IPP Tripeptide;H-ILE-PRO-PRO-OH;IPP, ACE-I Inhibitor;ISOLEUCYLPROLYLPROLINE;Isoleucine-Proline-Proline;Ile-Pro-Pro, ACE-I Inhibitor;L-Proline, L-isoleucyl-L-prolyl-
- 中文名:
- H-ILE-PRO-PRO-OH
- 中文别名:
- 三肽IPP;L-异亮氨酰-L-脯氨酰-L-脯氨酸
- CBNumber:
- CB3770717
- 分子式:
- C16H27N3O4
- 分子量:
- 325.4
- MOL File:
- 26001-32-1.mol
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H-ILE-PRO-PRO-OH化学性质
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沸点:
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572.6±50.0 °C(Predicted)
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密度:
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1.247±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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3.42±0.20(Predicted)
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序列:
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H-Ile-Pro-Pro-OH
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H-ILE-PRO-PRO-OH性质、用途与生产工艺
H-Ile-Pro-Pro-OH 是一种乳源三肽，抑制血管紧张素转换酶 (ACE) ，IC50 为 5 μM。具有抗高血压效果。
Ile-Pro-Pro (IPP; 1 nM, 0.1 μM, and 10 μM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs).
Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats
Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) .
Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice.
参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
H-ILE-PRO-PRO-OH
上下游产品信息
上游原料
下游产品
26001-32-1, H-ILE-PRO-PRO-OH 相关搜索:
- 多肽
- 目录肽
- 抑制剂
- 三肽IPP
- L-异亮氨酰-L-脯氨酰-L-脯氨酸
- 26001-32-1
- ISOLEUCYLPROLYLPROLINE
- Isoleucine-Proline-Proline
- L-Proline, L-isoleucyl-L-prolyl-
- IPP Tripeptide
- Ile-Pro-Pro, ACE-I Inhibitor
- Ile-Pro-Pro
- IPP, ACE-I Inhibitor
- H-ILE-PRO-PRO-OH