CYM 9484
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- CAS号:
- 1383478-94-1
- 英文名:
- N-[4-[(DiMethylaMino)sulfonyl]phenyl]-4-(hydroxydiphenylMethyl)-1-piperidinecarbothioaMide
- 英文别名:
- CYM 9484;N-(4-(N,N-Dimethylsulfamoyl)phenyl)-4-(hydroxydiphenylmethyl)piperidine-1-carbothioamide;N-[4-[(DiMethylaMino)sulfonyl]phenyl]-4-(hydroxydiphenylMethyl)-1-piperidinecarbothioaMide;1-Piperidinecarbothioamide, N-[4-[(dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-
- 中文名:
- CYM 9484
- 中文别名:
- 化合物 T10921;CYM 9484,NPY Y2受体拮抗剂;N-(4-(N,N-二甲基氨基磺酰基)苯基)-4-(羟基二苯基甲基)哌啶-1-硫代甲酰胺
- CBNumber:
- CB42696076
- 分子式:
- C27H31N3O3S2
- 分子量:
- 509.68
- MOL File:
- 1383478-94-1.mol
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CYM 9484化学性质
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储存条件:
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Store at RT
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溶解度:
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Soluble to 100 mM in DMSO
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形态:
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Powder
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CYM 9484性质、用途与生产工艺
CYM 9484 是一种选择性强效神经肽 Y (NPY) Y2 受体拮抗剂，IC50 值为 19 nM。
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NPYY
2
receptor
19 nM (IC
50
)
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SF-11 is a selective, brain-penetrant NPY Y2 receptor antagonist with an
IC
50
value of 190 nM. Systematically explore the SAR of the hit molecule SF-11 that leads to the identification of selective and highly potent small molecule NPY Y2 receptor antagonist CYM 9484 (Compound 16). CYM 9484 is 10-fold more potent than the hit molecule SF-11. CYM 9484 is prepared by the coupling of α,α-diphenylpiperidino-4-methanol with a variety of aryl isothiocyanates.
CYM 9484
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-107735 | CYM 9484
CYM 9484 | 1383478-94-1 | 5mg | 1500元 |
| 2024/01/25 | HY-107735 | CYM 9484 | | 10 mM * 1 mLin DMSO | 1680元 |
1383478-94-1, CYM 9484 相关搜索:
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
- 药靶配体
- C27H31N3O3S2
- CYM 9484,NPY Y2受体拮抗剂
- N-(4-(N,N-二甲基氨基磺酰基)苯基)-4-(羟基二苯基甲基)哌啶-1-硫代甲酰胺
- 化合物 T10921
- 1383478-94-1
- N-(4-(N,N-Dimethylsulfamoyl)phenyl)-4-(hydroxydiphenylmethyl)piperidine-1-carbothioamide
- 1-Piperidinecarbothioamide, N-[4-[(dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-
- CYM 9484
- N-[4-[(DiMethylaMino)sulfonyl]phenyl]-4-(hydroxydiphenylMethyl)-1-piperidinecarbothioaMide