142479-62-7
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- CAS号:
- 142479-62-7
- 英文名:
- DELTA-OPIOID RECEPTOR PEPTIDE TRIFLUOROACETATE SALT
- 英文别名:
- H-YPISL-OH;exorphin c;exorphin C trifluoroacetate;EXORPHIN C TRIFLUOROACETATE SALT;TYR-PRO-ILE-SER-LEU TRIFLUOROACETATE SALT;L-Leucine, L-tyrosyl-L-prolyl-L-isoleucyl-L-seryl-;inhibit,Gluten Exorphin C,Inhibitor,Opioid Receptor;DELTA-OPIOID RECEPTOR PEPTIDE TRIFLUOROACETATE SALT
- 中文名:
- 142479-62-7
- 中文别名:
- 化合物GLUTEN EXORPHIN C
- CBNumber:
- CB4303389
- 分子式:
- C29H45N5O8
- 分子量:
- 591.7
- MOL File:
- 142479-62-7.mol
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142479-62-7化学性质
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沸点:
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969.3±65.0 °C(Predicted)
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密度:
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1.264±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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3.30±0.10(Predicted)
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142479-62-7性质、用途与生产工艺
Gluten exorphin C 是一种源自谷朊粉的阿片肽。在 GPI 和 MVD 检测中，抑制 μ opioid 和 δ opioid 活性，IC50 值分别为 40 μM 和13.5 μM。
IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)
Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC
50
s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity.
142479-62-7
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142479-62-7, 142479-62-7 相关搜索:
- 多肽
- 标准品
- Opioid Peptides
- Other Opioid Peptides
- Peptides
- Amino Acids and Peptides
- BioChemical
- Biochemicals and Reagents
- C29H45N5O8
- C31H46F3N5O10
- 化合物GLUTEN EXORPHIN C
- 142479-62-7
- inhibit,Gluten Exorphin C,Inhibitor,Opioid Receptor
- H-YPISL-OH
- L-Leucine, L-tyrosyl-L-prolyl-L-isoleucyl-L-seryl-
- exorphin C trifluoroacetate
- DELTA-OPIOID RECEPTOR PEPTIDE TRIFLUOROACETATE SALT
- EXORPHIN C TRIFLUOROACETATE SALT
- exorphin c
- TYR-PRO-ILE-SER-LEU TRIFLUOROACETATE SALT