136564-67-5
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- CAS号:
- 136564-67-5
- 英文名:
- 1H-Indole-5-carboxamide, 3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-N-(4,4,4-trifluoro-2-methylbutyl)-
- 英文别名:
- LTD4 antagonist 1;LTD4 antagonist 1,LTD-4 antagonist 1;1H-Indole-5-carboxamide, 3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-N-(4,4,4-trifluoro-2-methylbutyl)-
- 中文名:
- 136564-67-5
- 中文别名:
- 化合物 T10057
- CBNumber:
- CB43339552
- 分子式:
- C31H32F3N3O5S
- 分子量:
- 615.6630896
- MOL File:
- 136564-67-5.mol
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136564-67-5化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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136564-67-5性质、用途与生产工艺
LTD4 antagonist 1 是一种有效有效的白三烯 D4 (leukotriene D4 , LTD4) 拮抗剂，Ki 值为 0.57 nM。
LTD
4
antagonist 1 (Compound 38b) exhibits a K
i
of 0.57 nM for displacement of [
3
H]LTD
4
on guinea pig lung membranes, a pK
B
of 9.93±0.14 versus LTE
4
on guinea pig trachea.
LTD
4
antagonist 1 (Compound 38b) exhibits a po ED
50
/iv ED
50
of 1.44 and 0.036 μmol/kg in LTD
4
-induced bronchoconstriction in guinea pigs.
136564-67-5
上下游产品信息
上游原料
下游产品
136564-67-5, 136564-67-5 相关搜索:
- 化合物 T10057
- 136564-67-5
- LTD4 antagonist 1,LTD-4 antagonist 1
- LTD4 antagonist 1
- 1H-Indole-5-carboxamide, 3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-N-(4,4,4-trifluoro-2-methylbutyl)-