ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT

生物活性靶点体外研究体内研究 ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 试剂级价格

CAS号:: 142439-94-9

英文名:: ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT

英文别名:: RP-CAMPS NA;CAMPS NA RP-ISOMER;RP-CAMPS SODIUM SALT;Rp cAMPS sodium salt,RpcAMPS sodium salt;SP-CYCLIC 3,5-HYDROGEN PHOSPHOROTHIOATE ADENOSINE SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER SODIUM SALT;ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT

中文名:: ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT

中文别名:

CBNumber:: CB4412021

分子式:: C10H13N5NaO5PS

分子量:: 369.27

MOL File:: Mol file

化学性质安全信息用途价格供应商 8

ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT化学性质

储存条件:: Store at -20°C, sealed storage, away from moisture and light

安全信息

ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT性质、用途与生产工艺

生物活性

Rp-cAMPS sodium salt，一种 cAMP 的类似物，是一种 cAMP 诱导的 PKA I 和 PKA II 活化 (Ki 分别为 12.5 µM 和 4.5 µM) 的有效的，竞争性拮抗剂。Rp-cAMPS sodium salt 耐磷酸二酯酶水解。

靶点

Ki: 6.05 µM (PKA I) and 9.75 µM (PKA II)

A membrane-permeable competitive cAMP antagonist (Rp-cAMPS) that blocks PKA activation by binding to the regulatory subunits without dissociating the kinase holoenzyme also inhibits synaptic plasticity but has no effect on normal synaptic transmission.

体内研究

Rp-cAMPS (10 μM, 15 min) decreases the monosynaptic EPSCs evoked at the PB-CeLC and BLA-CeLC synapses in slices from arthritic rats but not in control neurons from normal animals. The inhibitory effect of Rp-cAMPS is significant compared to predrug (ACSF) control values obtained in the same neurons.

ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 上下游产品信息

上游原料

下游产品

ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/01/25	HY-100530D	ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Rp-cAMPS sodium salt	142439-94-9	1mg	1800元
2024/01/25	HY-100530D	ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Rp-cAMPS sodium salt	142439-94-9	5mg	5000元

ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 生产厂家

全球有 8家供应商 ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
天津普西唐生物医药科技有限公司	010-60605840 15801484223	psaitong@jm-bio.com	中国	29834	58
TargetMol中国（陶术生物）	4008200310	marketing@tsbiochem.com	中国	24131	58
南通全益生物科技有限公司	0513-66337626 18051384581	sales@chemhifuture.com	中国	4030	58

142439-94-9, ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 相关搜索:

142439-94-9
Rp cAMPS sodium salt,RpcAMPS sodium salt
CAMPS NA RP-ISOMER
ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER SODIUM SALT
ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT
RP-CAMPS SODIUM SALT
RP-CAMPS NA
SP-CYCLIC 3,5-HYDROGEN PHOSPHOROTHIOATE ADENOSINE SODIUM SALT