肥大细胞脱粒肽
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- CAS号:
- 32908-73-9
- 英文名:
- MAST CELL DEGRANULATING PEPTIDE
- 英文别名:
- MCD;isulfide);MCD PEPTIDE;Peptide 401;IKCNCKRHVIKPHICRKICGKN-NH2;MCD PEPTIDE (APIS MELLIFERA);MAST CELL DEGRANULATING PEPTIDE;MAST CELL DEGRANULATING (MCD) PEPTIDE;mastcelldegranulatingpeptide(honeybee);MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
- 中文名:
- 肥大细胞脱粒肽
- 中文别名:
- MCD 肽;肥大细胞脱粒肽;蜜蜂肥大细胞脱粒肽
- CBNumber:
- CB4493264
- 分子式:
- C110H192N40O24S4
- 分子量:
- 2587.24
- MOL File:
- 32908-73-9.mol
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肥大细胞脱粒肽化学性质
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密度:
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1.50±0.1 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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肥大细胞脱粒肽性质、用途与生产工艺
Peptide 401 是一种有效的来源于蜂毒中的肥大细胞脱颗粒肽，抑制血管通透性。
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serotonin
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Histamine Receptor
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Peptide 401 substantially inhibits the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED
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of 401 is c. 0.1 mg/kg. The anti-inflammatory effect is assessed by measurement of the increased
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I-albumin content of an injected site in comparison with an uninjected contralateral site. Peptide 401 also suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins). Peptide 401 (MCD peptide) contains 22 residues and occurs in the venom of the common European honey bee to the extent of about 2% by weight . It has powerful anti-inflammatory activity (at doses as low as 0.1 mg/kg) in a variety of animal models, i.e., hind paw oedema in the rat induced by carrageenin or turpentine, adjuvant arthritis in the rat, and increased skin permeability in the rat resulting from subcutaneous injection of bradykinin, prostaglandin E1 kallikrein, histamine and 5- hydroxytryptamine (5-HT). It has a powerful degranulating effect on mast cells and involves the release of histamine and other pharmacologically active agents.
肥大细胞脱粒肽
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-12537 | MAST CELL DEGRANULATING PEPTIDE
Peptide 401 | 32908-73-9 | 500μg | 2800元 |
| 2024/01/25 | HY-12537 | MAST CELL DEGRANULATING PEPTIDE
Peptide 401 | 32908-73-9 | 1mg | 4800元 |
32908-73-9, 肥大细胞脱粒肽 相关搜索:
- 目录肽
- 标准品
- 细胞生物学
- Cell Biology
- Cell Signaling and Neuroscience
- BioChemical
- Monovalent Ion Channels
- Potassium Channel Modulators
- Ion Channels
- Voltage-gated Ion Channels
- C110H192N40O24S4
- 肥大细胞脱粒肽
- MCD 肽
- 蜜蜂肥大细胞脱粒肽
- 32908-73-9
- L-Aspartamide, L-isoleucyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinylglycyl-L-lysyl-, cyclic (3→15),(5→19)-bis(disulfide)
- Mast Cell Degranulating (MCD) Peptide
Peptide 401
- Peptide 401
- L-Ile-L-Lys-L-Cys(1)-L-Asn-L-Cys(2)-L-Lys-L-Arg-L-His-L-Val-L-Ile-L-Lys-L-Pro-L-His-L-Ile-L-Cys(1)-L-Arg-L-Lys-L-Ile-L-Cys(2)-Gly-L-Lys-L-Asn-NH2
- MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
- mastcelldegranulatingpeptide(honeybeereduced)cyclic(3-15),(5-19)-bis(d
- mastcelldegranulatingpeptide(honeybee)
- isulfide)
- MCD
- MCD PEPTIDE (APIS MELLIFERA)
- MCD PEPTIDE
- MAST CELL DEGRANULATING (MCD) PEPTIDE
- MAST CELL DEGRANULATING PEPTIDE (APIS MELLIFERA)
- MAST CELL DEGRANULATING PEPTIDE
- ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2
- IKCNCKRHVIKPHICRKICGKN-NH2
- H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 (RANDOM CYCLIZATION)
- H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2
- H-ILE-LYS-+CYS-ASN-++CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-+CYS-ARG-LYS- ILE-++CYS-GLY-LYS-ASN-NH2