盐酸地匹福林
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- CAS号:
- 64019-93-8
- 英文名:
- Dipivefrin hydrochloride
- 英文别名:
- Progate;Diopine;Pivalephrine;Dipivefrine HCL;hydrochloride,(+-)-este;dipivefrinhydrochloride;dipivefrinehydrochloride;Desvenlafaxine Impurity 5-d3;Dipivefrine hydrochloride CRS;dipivalylepinephrinehydrochloride
- 中文名:
- 盐酸地匹福林
- 中文别名:
- 盐酸地匹福林;盐酸二维弗林;盐酸地哌夫林;盐酸地匹福林盐酸盐;5-羟基色氨酸对照品;盐酸地匹福林 EP标准品;盐酸地匹福林 [64019-93-8];4-(1-羟基-2-(甲基氨基)乙基)-1,2-苯二醇二特戊酸酯盐酸盐
- CBNumber:
- CB4501444
- 分子式:
- C19H30ClNO5
- 分子量:
- 387.8982
- MOL File:
- 64019-93-8.mol
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盐酸地匹福林化学性质
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熔点:
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158-159°
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
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酸度系数(pKa):
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8.40(at 25℃)
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颜色:
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White to Off-White
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InChI:
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InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
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InChIKey:
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VKFAUCPBMAGVRG-UHFFFAOYSA-N
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SMILES:
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C1(OC(=O)C(C)(C)C)=CC(=CC=C1OC(=O)C(C)(C)C)C(O)CNC.Cl
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盐酸地匹福林性质、用途与生产工艺
Dipivefrin hydrochloride (Dipivefrine hydrochloride) 是一种抗青光眼前体药物，通过角膜中的酯酶水解为其活性化合物肾上腺素。
Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.
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Animal Model:
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Male 60-day-old CFW mice (23-28 g)
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Dosage:
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0.3 μg/kg, 1.0 μg/kg, 3.0 μg/kg, 10 μg/kg
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Administration:
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Intraperitoneal injection; post-training
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Result:
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Significantly enhanced retention of both inhibitory avoidance and Y-maze discrimination tasks in a dose-dependent manner.
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用途
降眼压药，用于治疗青光眼。
盐酸地匹福林
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2022/09/18 | HY-B1323 | 盐酸地匹福林
Dipivefrin hydrochloride | 64019-93-8 | 5 mg | 950元 |
| 2022/09/18 | HY-B1323 | 盐酸地匹福林
Dipivefrin hydrochloride | 64019-93-8 | 10mg | 1500元 |
盐酸地匹福林
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盐酸地匹福林国内生产厂家
64019-93-8, 盐酸地匹福林 相关搜索:
- API
- 药靶配体
- 原料药
- 标准品
- 中药对照品
- 盐酸地匹福林（标准品）
- 小分子抑制剂
- C19H30ClNO5
- C19H29NO5HCl
- 盐酸地匹福林盐酸盐
- 盐酸地哌夫林
- 5-羟基色氨酸对照品
- 盐酸二维弗林
- 盐酸地匹福林 EP标准品
- 盐酸地匹福林
- 4-(1-羟基-2-(甲基氨基)乙基)-1,2-苯二醇二特戊酸酯盐酸盐
- 盐酸地匹福林 [64019-93-8]
- 64019-93-8
- Desvenlafaxine Impurity 5-d3
- antiglaucoma,Dipivefrin hydrochloride,Dipivefrine,Inhibitor,prodrug,inhibit,epinephrine,Dipivefrin
- Dipivefrin Hydrochloride (1220302)
- Dipivefrin hydrochloride USP/EP/BP
- 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene bis(2,2-dimethylpropanoate) hydrochloride
- Dipivefrine hydrochloride CRS
- [2-(2,2-Dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride
- Propanoic acid, 2,2-dimethyl-, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester, hydrochloride, (+-)-
- Propanoic acid, 2,2-dimethyl-, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester, hydrochloride
- Pivalephrine
- Diopine
- Dipivefrine HCL
- Dipivaloyl epinephrine hydrochloride
- (±)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene dipivalate hydrochloride
- DIPIVEFRIN HYDROCHLORIDE (200 MG)
- Propanoic acid,2,2-diMethyl-, 1,1'-[4-[1-hydroxy-2-(MethylaMino)ethyl]-1,2-phenylene] ester,hydrochloride (1:1)
- Progate
- propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene
- hydrochloride,(+-)-este
- dipivefrinhydrochloride
- dipivefrinehydrochloride
- dipivalylepinephrinehydrochloride