刺五加苷B1
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- CAS号:
- 16845-16-2
- 英文名:
- ELEUTHEROSIDE B1(RG)
- 英文别名:
- ELEUTHEROSIDE B1(RG);2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-;2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-;6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one;Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit
- 中文名:
- 刺五加苷B1
- 中文别名:
- 刺五加苷B1;刺五加皂苷B1;胡萝卜苷/刺五加苷/胡萝卜甾醇
- CBNumber:
- CB4655037
- 分子式:
- C17H20O10
- 分子量:
- 384.34
- MOL File:
- 16845-16-2.mol
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刺五加苷B1化学性质
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沸点:
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675.0±55.0 °C(Predicted)
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密度:
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1.524±0.06 g/cm3(Predicted)
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储存条件:
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4°C, away from moisture and light
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酸度系数(pKa):
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12.65±0.70(Predicted)
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刺五加苷B1性质、用途与生产工艺
Eleutheroside B1，香豆素化合物，具有广谱的抗人流感病毒 (influenza virus) 作用，其IC50 值为 64-125μg/ml。Eleutheroside B1 通过 POLR2A 和 N-糖基化介导其抗流感活性。Eleutheroside B1 抑制多种趋化因子基因和流感病毒核蛋白 (NP) 基因的 mRNA 表达，且具有较低的细胞毒性。具有抗病毒、抗炎活性。
Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.
RT-PCR
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Cell Line:
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Virus-infected A549 cells
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Concentration:
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100 µg/ml
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Incubation Time:
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24 hours
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Result:
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The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.
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化学性质
白色结晶粉末，溶于氯仿，来源于刺五加Acanthopanax senticosus干燥根茎。
刺五加苷B1
上下游产品信息
上游原料
下游产品
16845-16-2, 刺五加苷B1 相关搜索:
- 标准品
- 胡萝卜苷/刺五加苷/胡萝卜甾醇
- 刺五加皂苷B1
- 刺五加苷B1
- 16845-16-2
- Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit
- 6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one
- 2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-
- 2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-
- ELEUTHEROSIDE B1(RG)