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NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
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- CAS号:
- 475221-20-6
- 英文名:
- AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
- 英文别名:
- NEP1-40;NOGO-66 (1-40);PubChem ID: 90488731;Nogo Extracellular Peptide;M.W. 4625.11 C206H324N56O65;NOGO EXTRACELLULAR PEPTIDE, 1-40;NOGO-66 (1-40) ANTAGONIST PEPTIDE;NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40;AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2;ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2
- 中文名:
- NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
- 中文别名:
- 抑制剂多肽NOGO-66 (1-40);AC-ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2
- CBNumber:
- CB5110481
- 分子式:
- C206H324N56O65
- 分子量:
- 4625.11
- MOL File:
- 475221-20-6.mol
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NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40化学性质
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储存条件:
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-20°C
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溶解度:
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H2O: 1 mg/mL
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形态:
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solid
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颜色:
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white
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水溶解性:
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Soluble to 1 mg/ml in water
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NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40性质、用途与生产工艺
NEP(1-40) 是 Nogo-66 受体 (NgR) 的肽类拮抗剂，通过限制髓蛋白抑制逆转损伤引起的小胶质细胞形态分布的改变。
NEP(1-40) (89 μg/kg, ip, 15 min and 19 h post-injury) administration further shifts distributions of microglia away from an injury-induced activated morphology towards greater proportions of rod and macrophage-like morphologies.
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Animal Model:
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74 male Sprague-Dawley rats (328-377 g).
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Dosage:
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89 μg/kg (97.5% PBS and 2.5% DMSO).
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Administration:
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IP, 15 min and 19 h post-injury.
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Result:
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Reduced NgR function immediately post-injury.
Increased number of amoeboid microglia/macrophages at 2 days post-injury
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NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-P1242 | NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
NEP(1-40) | 475221-20-6 | 1 mg | 4000元 |
| 2022/09/18 | HY-P1242 | NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
NEP(1-40) | 475221-20-6 | 5 mg | 13500元 |
NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
生产厂家
475221-20-6, NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40 相关搜索:
- Various Peptides
- 目录肽
- C206H324N56O65
- 抑制剂多肽NOGO-66 (1-40)
- AC-ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2
- 475221-20-6
- L-Serinamide,n2-acetyl-L-arginyl-L-isoleucyl-L-tyrosyl-L-Lysylglycyl-L-valyl-L-isoleucyl-L-glutaminyl-L-alanyl-L-isoleucyl-L-glutaminyl-L-Lysyl-L-seryl-L-a-aspartyl-L-a-glutamylglycyl-l-histidyl-l-pro
- Nogo Extracellular Peptide
- NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40
- PubChem ID: 90488731
- NOGO EXTRACELLULAR PEPTIDE, 1-40
- NOGO-66 (1-40) ANTAGONIST PEPTIDE
- NOGO-66 (1-40)
- NEP1-40
- M.W. 4625.11 C206H324N56O65
- AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
- ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2