(1S,3S)-1-氨基-1,3-环戊烷二甲酸
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- CAS号:
- 477331-06-9
- 英文名:
- (±)-trans-1-amino-1,3-dicarboxycyclopentane
- 英文别名:
- (±)-trans-1-amino-1,3-dicarboxycyclopentane;1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3R)-rel-;(±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS?, IUPAC);(±)-trans-1-Amino-1,3-dicarboxycyclopentane, cis-ACPD, (±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS(R), IUPAC)
- 中文名:
- (1S,3S)-1-氨基-1,3-环戊烷二甲酸
- 中文别名:
- (1S,3S)-1-氨基-1,3-环戊烷二甲酸
- CBNumber:
- CB51216290
- 分子式:
- C7H11NO4
- 分子量:
- 173.17
- MOL File:
- 477331-06-9.mol
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(1S,3S)-1-氨基-1,3-环戊烷二甲酸化学性质
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沸点:
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352.7±42.0 °C(Predicted)
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密度:
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1.452±0.06 g/cm3(Predicted)
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储存条件:
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Store at RT
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溶解度:
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Soluble to 100 mM in 1eq. NaOH
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形态:
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Powder
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酸度系数(pKa):
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2.11±0.40(Predicted)
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(1S,3S)-1-氨基-1,3-环戊烷二甲酸性质、用途与生产工艺
cis-ACPD 是一种有效的 NMDA 受体激动剂，IC50 值为 3.3 μM。同时也是一种选择性的 group II mGluR 激动剂，对 mGluR2 和 mGluR4 的 EC50 值分别为 13 μM 和 50 μM。
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NMDA
3.3 μM (IC
50
)
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mGluR2
13 μM (EC
50
)
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mGluR4
50 μM (EC
50
)
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cis-ACPD is a selective group II mGluR agonist, with EC
50
s of 13, 50, >300 and >300 μM for mGluR2, mGluR4, mGluR1 and mGluR5, respectively.
cis-ACPD (1-1000 µM; 60 min) stimulates hydrolysis of
3
H-phosphoinositide.
cis-ACPD (1-1000 mg/kg; i.p.) produces dose-related convulsions in rats.
(1S,3S)-1-氨基-1,3-环戊烷二甲酸
上下游产品信息
上游原料
下游产品
(1S,3S)-1-氨基-1,3-环戊烷二甲酸
生产厂家
477331-06-9, (1S,3S)-1-氨基-1,3-环戊烷二甲酸 相关搜索:
- (1S,3S)-1-氨基-1,3-环戊烷二甲酸
- 477331-06-9
- 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1R,3R)-rel-
- (±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS?, IUPAC)
- (±)-trans-1-Amino-1,3-dicarboxycyclopentane, cis-ACPD, (±)-trans-1-Aminocyclopentane-1,3-dicarboxylic acid (according to CAS(R), IUPAC)
- (±)-trans-1-amino-1,3-dicarboxycyclopentane