CAMALEXIN
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- CAS号:
- 135531-86-1
- 英文名:
- camalexin
- 英文别名:
- camalexin;Camalexine;Camalexin >=98% (HPLC);3-(Thiazol-2-yl)-1H-indole;1H-Indole, 3-(2-thiazolyl)-;3-(1,3-Thiazol-2-yl)-1H-indole;3-(1,3-Thiazol-2-yl)-1H-indole, camalexin;Phytoalexin,antifungal,Camalexin,antiproliferative,Bacterial,anticancer,ROS,Fungal,Inhibitor,Reactive Oxygen Species,inhibit,antibacterial,cruciferous
- 中文名:
- CAMALEXIN
- 中文别名:
- 植保素;35531-86-1;化合物CAMALEXIN;2-(1H-吲哚-3-基)噻唑;2-(1H-吲哚-3-基)噻唑(植保素)
- CBNumber:
- CB51384054
- 分子式:
- C11H8N2S
- 分子量:
- 200.26
- MOL File:
- 135531-86-1.mol
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CAMALEXIN化学性质
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沸点:
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424.8±47.0 °C(Predicted)
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密度:
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1.336±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO: soluble20mg/mL, clear
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酸度系数(pKa):
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15.49±0.30(Predicted)
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形态:
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powder
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颜色:
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white to light brown
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CAMALEXIN性质、用途与生产工艺
Camalexin 是一种植物抗毒素，是从 Camelina sativa 和 Arabidopsis（十字花科植物）中分离出来的，具有抗菌，抗真菌，抗增殖和抗癌活性。Camalexin 可诱导活性氧 (ROS) 的产生。
Reactive oxygen species (ROS)
Camalexin shows antiproliferative activity against a human breast cancer cell line.
For the oomycetes
Phytophthora
and
Pythium
Nep1-like proteins (necrosis and ethylene-inducing peptide 1-like proteins) are the initial triggers of Camalexin synthesis and formation of reactive oxygen species (ROS). ROS appear to be of general relevance for Camalexin formation. Chemical induction of ROS, such as by application of acifluorfen, coincided with Camalexin synthesis. In a screen for enhanced susceptibility to
Alternaria brassicicola
the
esa1
mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for
ESA1
is confirmed by the inability of
esa1
mutants to synthesize Camalexin in response to
Leptosphaeria maculans
. An additional mutant that exhibits greatly reduced Camalexin accumulation is
ups1
, which is isolated on the basis of diminished expression of a tryptophan biosynthetic enzyme.
CAMALEXIN
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-119502 | CAMALEXIN
Camalexin | 135531-86-1 | 5mg | 700元 |
| 2024/01/25 | HY-119502 | CAMALEXIN
Camalexin | 135531-86-1 | 10mM * 1mLin DMSO | 770元 |
135531-86-1, CAMALEXIN 相关搜索:
- 药靶配体
- 化工试剂
- 35531-86-1
- 2-(1H-吲哚-3-基)噻唑(植保素)
- 2-(1H-吲哚-3-基)噻唑
- 化合物CAMALEXIN
- 35531-86-1
- 植保素
- 135531-86-1
- Phytoalexin,antifungal,Camalexin,antiproliferative,Bacterial,anticancer,ROS,Fungal,Inhibitor,Reactive Oxygen Species,inhibit,antibacterial,cruciferous
- 3-(1,3-Thiazol-2-yl)-1H-indole
- 3-(1,3-Thiazol-2-yl)-1H-indole, camalexin
- Camalexin >=98% (HPLC)
- 1H-Indole, 3-(2-thiazolyl)-
- Camalexine
- 3-(Thiazol-2-yl)-1H-indole
- camalexin