192767-01-4
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- CAS号:
- 192767-01-4
- 英文名:
- L791943
- 英文别名:
- L791943;L791943,L-791943;Benzenemethanol, 4-[1-[3,4-bis(difluoromethoxy)phenyl]-2-(1-oxido-4-pyridinyl)ethyl]-α,α-bis(trifluoromethyl)-
- 中文名:
- 192767-01-4
- 中文别名:
- 化合物 T11810
- CBNumber:
- CB53339670
- 分子式:
- C24H17F10NO4
- 分子量:
- 573.39
- MOL File:
- 192767-01-4.mol
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192767-01-4化学性质
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沸点:
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561.6±50.0 °C(Predicted)
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密度:
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1.44±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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9.17±0.15(Predicted)
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192767-01-4性质、用途与生产工艺
L791943 是一种有效且有选择性的 Phosphodiesterase-4 (PDE4) 抑制剂,其 IC50 值 为 4.2 nM。
IC50: 4.2 nM (Phosphodiesterase-4)
The extent of metabolism of L791943 is evaluated in vitro in rat hepatocytes and compared to the data obtaine with CDP-840. In our standard incubation conditions, >98% of the parent drug remain in the case of L791943 whereas only 11% of CDP-840 is left intact.
192767-01-4
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192767-01-4, 192767-01-4 相关搜索:
- C24H17F10NO4
- 化合物 T11810
- 192767-01-4
- L791943,L-791943
- Benzenemethanol, 4-[1-[3,4-bis(difluoromethoxy)phenyl]-2-(1-oxido-4-pyridinyl)ethyl]-α,α-bis(trifluoromethyl)-
- L791943