酪里达唑
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- CAS号:
- 74772-77-3
- 英文名:
- CIGLITAZONE
- 英文别名:
- AD-4533;U-63287;ADD 3878;CIGLITIZONE;CIGLITAZONE;CIGLITLZONE;Ciglitazona;CIGLITAZONE USP/EP/BP;Ciglitazone Solution, 100ppm;CIGLITAZONE(SUBJECTTOPATENTFREE)
- 中文名:
- 酪里达唑
- 中文别名:
- 环格列酮;酪里达唑;化合物 T19710;环格列酮溶液, 100PPM;乙腈中环格列酮溶液,100ΜG/ML;5-[[4-[(1-甲基环己基)甲氧基]苯基]甲基]-2,4-噻唑烷二酮
- CBNumber:
- CB5416208
- 分子式:
- C18H23NO3S
- 分子量:
- 333.45
- MOL File:
- 74772-77-3.mol
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酪里达唑化学性质
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熔点:
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130-131°C
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沸点:
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504.5±23.0 °C(Predicted)
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密度:
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1.189±0.06 g/cm3(Predicted)
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储存条件:
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Store at RT
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溶解度:
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Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
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形态:
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Tan solid
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酸度系数(pKa):
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6.36±0.50(Predicted)
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颜色:
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Tan
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稳定性:
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Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
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酪里达唑性质、用途与生产工艺
酪里达唑属于噻唑烷二酮(thiazolidinedione,TZDs)类药物，是PPARγ的人工合成配体，对PPARγ很高的选择性，除了具有胰岛素增敏的作用外，还具有调控炎症、抑制细胞增殖、诱导细胞凋亡、调节细胞代谢等方面发挥作用。
在六氢吡啶作用下,对羟基苯甲醛和2,4-噻唑烷二酮缩合生成5-[(4-羟苯基)亚甲基]-2,4-噻唑烷二酮,经钯炭催化氢化还原生成5-[(4-羟苯基)甲基]-2,4-噻唑烷二酮,再和氢氧化钾反应生成相应的钾盐,然后与5-乙基-2-羟乙基吡啶和甲基磺酰氯反应得到的磺酸酯作用生成酪里达唑,最后用盐酸酸化得到其盐酸盐
酪里达唑
上下游产品信息
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-W011220 | 酪里达唑
Ciglitazone | 74772-77-3 | 5 mg | 880元 |
酪里达唑
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74772-77-3, 酪里达唑 相关搜索:
- Intracellular receptor
- API's
- Sulfur & Selenium Compounds
- Metal Isotopes
- Active Pharmaceutical Ingredients
- Gene Regulation and Expression
- PPAR and RXR Regulators
- Cell Biology
- Cell Signaling and Neuroscience
- BioChemical
- C18H23NO3S
- 化合物 T19710
- 乙腈中环格列酮溶液,100ΜG/ML
- 环格列酮溶液, 100PPM
- 环格列酮
- 5-[[4-[(1-甲基环己基)甲氧基]苯基]甲基]-2,4-噻唑烷二酮
- 酪里达唑
- 74772-77-3
- Ciglitazona
- CIGLITAZONE USP/EP/BP
- Ciglitazone Solution in Acetonitrile, 100μg/mL
- 2,4-Thiazolidinedione, 5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-
- Ciglitazone Solution, 100ppm
- Ciglitazone - CAS 74772-77-3 - Calbiochem
- AD-4533
- 5-[p-[2,2-(Pentane-1,5-diyl)propyloxy]benzyl]thiazolidine-2,4-dione
- CIGLITLZONE
- CIGLITAZONE(SUBJECTTOPATENTFREE)
- CIGLITIZONE
- CIGLITAZONE
- ADD 3878
- 5-[[4-[(1-METHYLCYCLOHEXYL)METHOXY]PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
- (+/-)-5-[4-(1-METHYLCYCLOHEXYLMETHOXY)BENZYL]-THIAZOLIDINE-2,4-DIONE
- U-63287
- 5-((4-((1-methylcyclohexyl)methoxy)phenyl)methyl)-4-thiazolidinedione