唾液酸化酶X
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- CAS号:
- 98603-84-0
- 英文名:
- SIALYL LEWIS X
- 英文别名:
- S LEX;SSEA 1;3′-SLeX;Lewis Sugars;SIALYL LEWIS X;Sialyl Lex tri;3'-SIALYL LEWIS;3'-SIALYL-LEWISX;SLEX, SODIUM SALT;Sialyl Lewisx (S Lex)
- 中文名:
- 唾液酸化酶X
- 中文别名:
- 唾液酸化酶X;3′-路易斯寡糖-X;3-路易斯寡糖-X四糖;唾液素LEWIS X抗原四糖;唾液酸化LEWIS-X(SLE-X)四糖
- CBNumber:
- CB5472086
- 分子式:
- C31H52N2O23
- 分子量:
- 820.74
- MOL File:
- 98603-84-0.mol
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唾液酸化酶X化学性质
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熔点:
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157 - 161°C
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储存条件:
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-20°C
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溶解度:
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Methanol (Slightly), Water (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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稳定性:
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Store in freezer
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唾液酸化酶X性质、用途与生产工艺
Sialyl-Lewis X (sLeX) 是一种唾液酶酸化的聚四糖，是一种内源性抗原 (antigen)。Sialyl-Lewis X 是选择素 E-、P- 和 L- 的高亲和力配体 (ligand)。Sialyl-Lewis X 与 ELAM-1 和 CD62 结合，具有抑制 CD62 介导的炎症部位中性粒细胞募集的能力。
Sialyl-Lewis X is a high-affinity ligand of CD62, Antibodies [mAb CSLEX (IgM; anti-sLeX)] to sLeX inhibit CD62-mediated binding of HL-60 cells to activated platelets.Liposomes containing glycolipids with the sLeX structure prevents adhesion of HL-60 cells and human neutrophils. HL-60 cell adhesion is partially inhibited (50%) by liposomes containing Lex at 5 μg/ml. However, sLeX liposomes give maximal inhibition at only 1 ug/ml. sLeX liposomes inhibits adhesion with a 10-fold higher affinity than Lex liposomes.CD62 binding of neutrophils to activated platelets is inhibited a soluble human milk oligosaccharide that contains the LeX structure. the sLeX sugar is a 30-fold more potent inhibitor than the nonsialylated Lex sugar, which requires 2 μg/ml and 54 μg/ml to achieve 50% inhibition of neutrophil adhesion, respectively.
唾液酸化酶X
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-W020790 | 唾液酸化酶X
Sialyl-Lewis X | 98603-84-0 | 1mg | 4200元 |
| 2023/03/20 | HY-W020790 | 唾液酸化酶X
Sialyl-Lewis X | 98603-84-0 | 5mg | 16500元 |
唾液酸化酶X
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98603-84-0, 唾液酸化酶X 相关搜索:
- Oligosaccharide Compounds
- Oligosaccharides
- 生化试剂
- 寡糖-血型寡糖
- 对照品
- 寡糖
- 碳水化合物
- 翻译后修饰
- Proteomics and Protein Expression
- Proteomics
- Post-translational Modification
- Carbohydrate Standards
- Carbohydrate Analysis
- BioChemical
- 3′-路易斯寡糖-X
- 3-路易斯寡糖-X四糖
- 唾液素LEWIS X抗原四糖
- 唾液酸化LEWIS-X(SLE-X)四糖
- 唾液酸化酶X
- 98603-84-0
- SIALYL LEWIS X USP/EP/BP
- D-Glucose, O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-
- Sialyl LewisX (sLeX) tetraose
- Sialyl Lewisx (S Lex)
- 3′-SLeX
- SSEA 1
- Sialyl Lex tri
- Neu5Ac2-α-3Gal1-b-4[Fuc1-α-3]GlcNAc,
O-(5-AcetaMido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-2-α-3-O-(b-D-galactopyranosyl)-1-b-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-acetaMido-2-deoxy-D-glucopyranose]
- Lewis Sugars
- 3μ-SLeX, α-NeuNAc-(2-3)-β-D-Gal-(1-4)(α-L-Fuc-[1-3])-D-GlcNAc
- Neu5Ac2-α-3Gal1-β-4[Fuc1-α-3]GlcNAc, O-(5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-2-α-3-O-(b-D-galactopyranosyl)-1-β-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-acetamido-2-deoxy-D-glucopyranose]
- 3''SIALYL LEWIS X [NEUNAC-ALPHA2-3GAL-SS1-4(FUC-ALPHA1-3)GLCNAC]
- (2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4R,5R)-5-acetamido-1,2-dihydroxy-6-oxo-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
- α-neunac-(2→3)-β-d-gal-(1→4)(α-l-fuc-[1→3])-d-glcnac
- Neu5Ac2-a-3Gal1-b-4[Fuc1-a-3]GlcNAc,O-(5-Acetamido-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonic Acid)-2-a-3-O-(b-D-galactopyranosyl)-1-b-4-O-[(a-L-fucopyranosyl)-1-a-3]-2-acetamido-2-deoxy-D-glucopyranose]
- O-(5-Acetamido-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonicacid)-2-a-3-O-(b-D-galactopyranosyl)-1-beta-4-O-[
- S LEX
- SLEX, SODIUM SALT
- SIALYL LEWIS X, SODIUM SALT
- SIALYL LEWIS X
- O-(5-ACETAMIDO-3,5-DIDEOXY-D-GLYCERO-ALPHA-D-GALACTO-2-NONULOPYRANOSYLONIC ACID)-2-A-3-O-(BETA-D-GALACTOPYRANOSYL)-1-B-4-O-[(A-L-FUCOPYRANOSYL)-1-A-3]-2-ACETAMIDO-2-DEOXY-D-GLUCOPYRANOSE
- NEU5AC2-A-3GAL1-B-4[FUC1-A-3]GLCNAC
- NEUNAC-ALPHA2-3GAL-BETA1-4(FUC-ALPHA1-3)GLCNAC
- NEU5AC-ALPHA2,3GALBETA1,4(FUCALPHA1,3)GLCNAC, SODIUM SALT
- NEU5AC-ALPHA2,3GAL-BETA1,4(FUC-ALPHA1,3)GLCNAC
- 3'-SIALYL-LEWIS-X TETRASACCHARIDE
- 3'-SIALYL-LEWISX
- 3'-SIALYL LEWIS
- 5-ACETAMIDO-3,5-DI-DEOXY-D-GLYCERO-ALPHA-D-GALACTO-2-NOULOPYRANOSYL(2-3)-BETA-D-GALACTOPYRANOSYL(1-4)-[ALPHA-L-FUCOPYRANOSYL(1-4)]-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE